The Norwegian Exercise in Atrial Fibrillation Trial - An Open-label, Multicenter Randomized Controlled Trial Comparing an eHealth-based Exercise Intervention With Usual Care After 12 Months Follow-up
Sponsor: Norwegian University of Science and Technology
Trial Details
| Condition | Atrial Fibrillation |
| Intervention | Supervised home-based exercise; Usual care |
| Phase | NA |
| Status | Completed |
| Participants | 300 |
| Est. Completion | 4 July 2025 |
| Last Updated | 8 July 2026 |
Primary Outcome
Change in health-related quality of life and symptoms; Total time-in-AF(%)
Eligibility Criteria
Inclusion Criteria
Inclusion Criteria: * Signed informed consent * Diagnosed with paroxysmal or persistent AF in hospital registries * In sinus rhythm at baseline screening * Report \<75 minutes per week of vigorous and/or \<150 minutes of moderate intensity exercise the last three months * Use a smartphone Exclusion Criteria: * Permanent AF or persistent AF with at least one continuous episode lasting ≥3 months the last year * AF as a complication of acute coronary syndromes, cardiothoracic surgery or infections * Planned ablation procedure next 12 months or ablated last 6 months without known recurrence * Unstable coronary heart disease * De-compensated heart failure * Left ventricular ejection fraction \<40% * At least moderate to severe mitral or aortic pathology, or aortic aneurysms clinically incompatible with safe exercise * Moderate to severe chronic obstructive pulmonary disease (GOLD group C+D) * Ongoing severe cancer or active cancer treatment * Pacemaker or ICD * Pregnancy * Alcohol or drug abuse * Cognitive or serious psychiatric disease that may impede protocol compliance * Physical impairments or diseases hindering exercise or making exercise contraindicated * Resident of nursing home or other institution * Participation in conflicting research studies (i.e. lifestyle interventions)
Trial Sites
Countries
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