Evaluation of a Proactive Identification and Digital Mental Health Intervention Approach to Address Unmet Psychosocial Needs of Individuals Living With Likely Incurable Cancer
Sponsor: Medical University of South Carolina
Trial Details
| Condition | Depression, Depressive Symptoms, Cancer |
| Intervention | Behavioral Activation Therapy App; Treatment as Usual |
| Phase | NA |
| Status | Recruiting |
| Participants | 279 |
| Est. Completion | 1 Sept 2028 |
| Last Updated | 22 May 2026 |
Primary Outcome
Change in Depression
Eligibility Criteria
Inclusion Criteria
Inclusion Criteria: * Age \> 18 years * ILLIC (as determined during manual chart review) * Elevated depressive symptoms, defined as a score of ≥ 8 on the PHQ-9 * Current owner of an iOS- or Android-compatible smartphone * Willingness to utilize a mobile app for the treatment of depressed mood (response of "yes" on yes/no item) * Have a valid e-mail address that is checked regularly or have regular access to text messages (to access follow-up assessments) * English language fluency Exclusion Criteria: * Current suicidal ideation at study screening, defined as a response greater than or equal to 1 on item nine of the PHQ-9 * Severe cognitive impairment that precludes completion of informed consent. For the purposes of assessing eligibility, this criterion is operationalized as: * Prior diagnosis of dementia, or Major Neurocognitive Disorder indicated either via self-report or in the EHR; or * Self-report of cognitive difficulties that impair functional independence
Trial Sites
Countries
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