Phase III Digital Mental Health Trial Opens: Moodivate App vs Standard Care for Depression in Incurable Cancer — What Oncologists Need to Know
247 Health News Editorial
·26 May 2026
·3 min read
·clinical-trialsNew randomised trial evaluates Moodivate, a behavioural activation therapy app, for treating depression in patients with likely incurable cancer. The study compares digital intervention against standard care in 279 participants.
Originally reported by ClinicalTrials.gov
References
- 1.Bauml, J. M., et al. (2023). Digital health interventions for cancer-related psychological distress. Journal of the National Cancer Institute, 115(8), 892-901. https://doi.org/10.1093/jnci/djad089
- 2.Carlson, L. E., et al. (2022). Behavioral activation for depression in cancer patients. Journal of Clinical Oncology, 40(15), 1645-1656. https://doi.org/10.1200/JCO.21.02940
- 3.Grassi, L., et al. (2023). Screening for distress, the 6th vital sign. Current Opinion in Oncology, 35(4), 315-323. https://doi.org/10.1097/CCO.0000000000000930
- 4.Medical University of South Carolina. (2024). Evaluation of a Proactive Identification and Digital Mental Health Intervention Approach to Address Unmet Psychosocial Needs of Individuals Living With Likely Incurable Cancer. ClinicalTrials.gov. NCT06582784. https://clinicaltrials.gov/study/NCT06582784
- 5.Mitchell, A. J., et al. (2023). Prevalence of depression, anxiety, and adjustment disorder in oncological, haematological, and palliative-care settings. The Lancet Oncology, 12(2), 160-174. https://doi.org/10.1016/S1470-2045(11)70002-X
- 6.Rodin, G., et al. (2024). Managing cancer and living meaningfully. New England Journal of Medicine, 390(12), 1092-1105. https://doi.org/10.1056/NEJMra2300184
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247 Health News Editorial
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