Not_yet_recruitingNCT07591779

Study of the Relationship Between Clinical and Functional Characteristics of Patients With CMT1A Disease and Their Level of Physical Activity at Home Measured Using Portable Electronic Sensors

Sponsor: University Hospital, Limoges

Trial Details

ConditionCharcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary, Motor Activity, Walking, Difficulty, Neuromuscular Diseases
StatusNot_yet_recruiting
Participants60
Est. Completion15 Apr 2027
Last Updated22 May 2026

Primary Outcome

Pearson/Spearman r: daily step count (ActiGraph) vs. CMT-FOM total score; Pearson/Spearman r: daily step count (ActiGraph) vs. CMT-FOM total score; Pearson/Spearman r: daily activity counts (ActiGraph) vs. CMT-FOM total score; Pearson/Spearman r: daily activity counts (ActiGraph) vs. CMT-FOM total score; Pearson/Spearman r: daily sedentary time (ActiGraph) vs. CMT-FOM total score; Pearson/Spearman r: daily sedentary time (ActiGraph) vs. CMT-FOM total score; Pearson/Spearman r: composite sensor score vs. CMT-FOM sub-scores; Pearson/Spearman r: composite sensor score vs. CMT-FOM sub-scores

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: 1. Age ≥ 18 years 2. Genetically confirmed diagnosis of CMT1A (PMP22 duplication on chromosomal analysis) 3. Followed at the National Reference Centre for Rare Peripheral Neuropathies (Service de Neurologie, CHU de Limoges) and/or having undergone gait analysis at the Quantified Movement Analysis Laboratory (Laboratoire d'AQM), Service de Médecine Physique et de Réadaptation, CHU de Limoges 4. Ability to walk independently (with or without walking aids) 5. Informed consent obtained 6. Affiliated to French social security system Exclusion Criteria: 1. Other associated neurological condition that could independently affect walking or motor activity 2. Inability to wear the sensor device (skin allergy, sensory intolerance) 3. Inability to comply with study procedures (cognitive impairment, no fixed domicile) 4. Participation in another interventional study during the same period 5. Pregnant or breastfeeding women 6. Patients under legal protection (guardianship or curatorship)

Trial Sites

Countries

France
View Registry Entry

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