Study of the Relationship Between Clinical and Functional Characteristics of Patients With CMT1A Disease and Their Level of Physical Activity at Home Measured Using Portable Electronic Sensors
Sponsor: University Hospital, Limoges
Trial Details
| Condition | Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary, Motor Activity, Walking, Difficulty, Neuromuscular Diseases |
| Status | Not_yet_recruiting |
| Participants | 60 |
| Est. Completion | 15 Apr 2027 |
| Last Updated | 22 May 2026 |
Primary Outcome
Pearson/Spearman r: daily step count (ActiGraph) vs. CMT-FOM total score; Pearson/Spearman r: daily step count (ActiGraph) vs. CMT-FOM total score; Pearson/Spearman r: daily activity counts (ActiGraph) vs. CMT-FOM total score; Pearson/Spearman r: daily activity counts (ActiGraph) vs. CMT-FOM total score; Pearson/Spearman r: daily sedentary time (ActiGraph) vs. CMT-FOM total score; Pearson/Spearman r: daily sedentary time (ActiGraph) vs. CMT-FOM total score; Pearson/Spearman r: composite sensor score vs. CMT-FOM sub-scores; Pearson/Spearman r: composite sensor score vs. CMT-FOM sub-scores
Eligibility Criteria
Inclusion Criteria
Inclusion Criteria: 1. Age ≥ 18 years 2. Genetically confirmed diagnosis of CMT1A (PMP22 duplication on chromosomal analysis) 3. Followed at the National Reference Centre for Rare Peripheral Neuropathies (Service de Neurologie, CHU de Limoges) and/or having undergone gait analysis at the Quantified Movement Analysis Laboratory (Laboratoire d'AQM), Service de Médecine Physique et de Réadaptation, CHU de Limoges 4. Ability to walk independently (with or without walking aids) 5. Informed consent obtained 6. Affiliated to French social security system Exclusion Criteria: 1. Other associated neurological condition that could independently affect walking or motor activity 2. Inability to wear the sensor device (skin allergy, sensory intolerance) 3. Inability to comply with study procedures (cognitive impairment, no fixed domicile) 4. Participation in another interventional study during the same period 5. Pregnant or breastfeeding women 6. Patients under legal protection (guardianship or curatorship)
Trial Sites
Countries
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