ActiveNANCT06964412

A Phase II Randomized Study of the Use of Artificial Intelligence Generated Contours in Ultrasound-based Prostate HDR Brachytherapy

Sponsor: Brigham and Women's Hospital

Trial Details

Condition	Prostate Cancer
Intervention	Artificial-intelligence (AI)
Phase	NA
Status	Active
Participants	36
Est. Completion	30 May 2027
Last Updated	29 May 2026

Primary Outcome

Clinically approved contour vs. Manual and AI assisted contours

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: * 18 years of age and older * Deemed suitable candidates for whole gland HDR prostate brachytherapy under general anesthesia as a monotherapy, boost or salvage treatment. Exclusion Criteria: * Prior permanent seed LDR brachytherapy implant * Prior transurethral resection of the prostate (TURP) * Presence or insertion of a rectal spacer * Focal HDR brachytherapy treatment i.e. not whole prostate

Trial Sites

Countries

United States

View Registry Entry

Related Analysis

Phase II Trial Evaluates AI-Assisted Contouring for Prostate HDR Brachytherapy — Precision Radiation Planning Under Investigation

A Phase II trial at Brigham and Women's Hospital is evaluating AI-assisted prostate contouring for HDR brachytherapy planning. The study compares AI-generated contours with traditional manual methods to improve treatment precision and workflow efficiency.

Read full article →

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