A Personalized Medicine Prehabilitation Intervention Delivered Using Wearable Mobile Devices to Improve Cognitive Function in Elective Joint Replacement Surgery

Inclusion Criteria

Inclusion Criteria: * Adults scheduled for elective arthroplasty; * ≥55 years of age; * Capable of giving informed consent; * Willing to comply either to undergo prehabilitation (cases) or standard preoperative care (control); * Own a smartphone. Exclusion Criteria: * Patients with bilateral or revision surgeries; * Diagnosis of pre-existing dementia; * Test result of \<20 in the MoCA indicating moderate to severe dementia; * Diagnosis of acute stroke; * Diagnosis of neurologic injury; * Current alcohol (more than 2 drinks a day with last drink within the past 3 days) or substance abuse (positive urine dip test for illicit drugs) history at risk of postoperative withdrawal; * Active diagnosis of alcohol or substance abuse; * Recent travel across more than two (2) time zones (within the past month); * Planned travel across more than two (2) time zones during the planned study activities; * Subjects, who have received an experimental drug, used an experimental medical device within 30 days prior to screening, or who gave a blood donation of ≥ one pint within 8 weeks prior to screening; * Subjects without access to WiFi in their or close to home or at work.