Full Title: Sepsis Early Prediction System Score (SEPSys Score) and RESCUE Score Multi-Site, Two-Intervention, Cluster-Randomized, Factorial Stepped-Wedge Pragmatic Clinical Trial at the University of Mayland Medical System

Inclusion Criteria

Hospital Unit Inclusion Criteria: * Units are part of a member hospital of the University of Maryland Medical System (UMMS) * Units treat inpatient patients * Units agree to participate in the study General Encounter Inclusion Criteria: * Encounter is on a participating inpatient unit * Encounter is associated with a bedded patient in the hospital * Encounter is associated with an adult (at least 18 years of age at time of admission) Additional SEPSys Encounter Inclusion Criteria: • Encounter has a SEPSys Score Additional RESCUE Encounter Inclusion Criteria: • Encounter has a RESCUE Score Exclusion Criteria: Hospital Unit Exclusion Criteria: * Unit treats exclusively outpatients or is located in an outpatient setting * Unit treats primarily or exclusively pediatric patients (patients under the age of 18 years old) * Unit treats exclusively psychiatric patients Additional SEPSys Encounter Exclusion Criteria: * Encounter is with OB for a normal delivery and the patient has yet to give birth. This encounter can become eligible once the patient has given birth. * Encounter is admitted with a diagnosis of sepsis * Sepsis was already diagnosed during the encounter This encounter will have been eligible until the patient began showing clinical signs or symptoms of sepsis or received a diagnosis of sepsis. Once they have a diagnosis or clinical signs or symptoms of sepsis, their SEPSys Score will no longer be updated. Data will continue to be collected on time of laboratory orders and treatments. Additional RESCUE Encounter Exclusion Criteria: • Encounter is admitted with a high RESCUE Score (RESCUE Score of 4)