Not_yet_recruitingNANCT06872346

Personalized Risk-based Follow-up of Cervical Cancer Screening in Practice (PREDICT), Randomized Control Trial

Sponsor: Massachusetts General Hospital

Trial Details

ConditionCervical Cancer Screening
InterventionVisit-based IT reminders to patients and practitioners; Population outreach
PhaseNA
StatusNot_yet_recruiting
Participants7,500
Est. Completion15 June 2028
Last Updated26 May 2026

Primary Outcome

Primary effectiveness outcome

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria, Individuals who: * have a cervix and are 21-70 years old * receive care at a participating primary care practice (i.e. PCP team visit within past 3 years) * have had a Pap and/ or HPV test within the past 3.5 years * has a CCSM result that suggest a 5-year risk of developing CIN3+ that warrants surveillance at 1 or 3 years, diagnostic colposcopy, or treatment (i.e., above average risk). Inclusion of those up to age 70 is intended to identify individuals whose prior history does not meet screening exit criteria, and warrants surveillance or diagnostic care even though women with adequate prior screening can stop at age 65 Exclusion Criteria Individuals who: * were diagnosed with cervical cancer/ CIN3+ prior to the most recent screening Pap or HPV test * have had their cervix removed * are not English or Spanish-speaking.

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