Not_yet_recruitingNANCT07612436

AI-empowered Nudge to Improve Colonoscopy Uptake (AINC): A Pragmatic Cluster-Randomized Trial

Sponsor: Fudan University

Trial Details

Condition	Colorectal Neoplasms, Colonoscopy
Intervention	AI-empowered nudge (AINC) strategy; Usual Care
Phase	NA
Status	Not_yet_recruiting
Participants	1,680
Est. Completion	1 Oct 2026
Last Updated	4 June 2026

Primary Outcome

Uptake of colonoscopy

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: * Aged 45-74 years; * Test positive on the Colorectal Cancer Risk Assessment Scale and the immunochemical fecal occult blood test; * In good general health, mentally competent ④ Provide informed consent. Exclusion Criteria: * History of colorectal resection; ② Previous diagnosis of cancer or currently undergoing any cancer-related treatment; * Underwent a colonoscopy or sigmoidoscopy within the past 5 years; ④ Contraindications to colonoscopy,(e.g. severe cardiac, cerebral, lung diseases, or renal dysfunction).

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Related Analysis

Phase III Cluster-RCT Opens: AI-Powered Nudge Strategy vs Standard Care for Colonoscopy Uptake in High-Risk Patients — What Clinicians Need to Know

New cluster-randomised trial investigates AI-powered nudge strategies to improve colonoscopy uptake in high-risk patients aged 45-74. The AINC trial combines personalised AI chatbot education with behavioural nudges, addressing critical gaps in colorectal cancer screening compliance.

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