Not_yet_recruitingNANCT07051148

Efficacy of a Personalized, Response-based Transdiagnostic Intervention for Emotional Disorders Delivered Via the Internet: A Protocol for an Adaptive Randomized Controlled Trial

Sponsor: Universitat Jaume I

Trial Details

Condition	Emotional Disorders, Anxiety, Depression, Unipolar
Intervention	UJI Online Transdiagnostic Protocol; UJI On Line Transdiagnostic Hibrid Protocol
Phase	NA
Status	Not_yet_recruiting
Participants	366
Est. Completion	1 Dec 2029
Last Updated	27 May 2026

Primary Outcome

Clinical Outcomes in Routine Evaluation (CORE-34, Evans et al., 2002); Clinical Outcomes in Routine Evaluation 10 (CORE 10, Barkham et al., 2013)

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: * Spanish speakers * OASIS score +/= 8 * ODSIS score +/= 7 * Access to Internet * Email Exclusion Criteria: * Severe mental disorder: schizophrenia/bipolar disorder * Active substance abuse * High suicide risk * Ongoing psychological/pharmacological treatment * Interfering physical illness

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Related Analysis

Adaptive RCT Opens: Personalised Internet-Delivered Transdiagnostic Therapy for Anxiety and Depression — Response-Based Treatment Optimisation

New adaptive RCT investigates personalised internet-delivered therapy for anxiety and depression, using early treatment response to guide intervention intensity. 366 participants will receive response-based treatment allocation.

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