CompletedNANCT04214210

The DIALOGUE Study: Using Digital Health to Improve Care for Families With Predisposition to Hereditary Cancer

Sponsor: University of Basel

Trial Details

ConditionHereditary Cancer, Breast Cancer, Ovarian Cancer
InterventionAdapted Family Gene Toolkit; Targeted intervention
PhaseNA
StatusCompleted
Participants128
Est. Completion31 Dec 2025
Last Updated13 May 2026

Primary Outcome

Profile of Mood States (POMS); Change in proportion of informed relatives; Informing Relatives Inventory; Intention to have genetic testing; Reach; Effectiveness; Adoption; Implementation; Maintenance

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: * Speak and read German, French, Italian, English, or Korean * Residence in Switzerland or in Korea * Has been identified with a pathogenic variant associated with HBOC or * Has ≥1 first-, second-degree relative or first cousing with HBOC * Mentally able to provide informed consent Exclusion Criteria: * mutation carriers who do not have any family members; * husbands and partners, although they may play an important role in decisions for genetic testing and risk management of disease, will not be included in the study; * participants with a prior diagnosis of a mental disease and those unable to provide informed consent; * those physically ill and not being able to complete a baseline survey; * those without access to the web through a computer, tablet, or smartphone.

Trial Sites

Countries

Switzerland
View Registry Entry

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