The DIALOGUE Study: Using Digital Health to Improve Care for Families With Predisposition to Hereditary Cancer
Sponsor: University of Basel
Trial Details
| Condition | Hereditary Cancer, Breast Cancer, Ovarian Cancer |
| Intervention | Adapted Family Gene Toolkit; Targeted intervention |
| Phase | NA |
| Status | Completed |
| Participants | 128 |
| Est. Completion | 31 Dec 2025 |
| Last Updated | 13 May 2026 |
Primary Outcome
Profile of Mood States (POMS); Change in proportion of informed relatives; Informing Relatives Inventory; Intention to have genetic testing; Reach; Effectiveness; Adoption; Implementation; Maintenance
Eligibility Criteria
Inclusion Criteria
Inclusion Criteria: * Speak and read German, French, Italian, English, or Korean * Residence in Switzerland or in Korea * Has been identified with a pathogenic variant associated with HBOC or * Has ≥1 first-, second-degree relative or first cousing with HBOC * Mentally able to provide informed consent Exclusion Criteria: * mutation carriers who do not have any family members; * husbands and partners, although they may play an important role in decisions for genetic testing and risk management of disease, will not be included in the study; * participants with a prior diagnosis of a mental disease and those unable to provide informed consent; * those physically ill and not being able to complete a baseline survey; * those without access to the web through a computer, tablet, or smartphone.
Trial Sites
Countries
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