Health Technology/clinical-trials

DIALOGUE Study Completes: Digital Platform Shows Promise for Hereditary Cancer Family Communication — Implications for Australian Practice

247 Health News Editorial

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20 May 2026

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4 min read

·clinical-trials

The completed DIALOGUE study demonstrates how digital health platforms can improve family communication about hereditary breast and ovarian cancer predisposition. Results from 128 participants across Switzerland and Korea provide evidence for technology-assisted cascade genetic testing approaches.

Originally reported by ClinicalTrials.gov

References

  1. 1.University of Basel. (2024). The DIALOGUE Study: Using Digital Health to Improve Care for Families With Predisposition to Hereditary Cancer. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT04214210
  2. 2.Suthers, G. K., Armstrong, J., McCormack, J., & Trott, D. (2006). Letting the family know: balancing ethics and effectiveness when notifying relatives about genetic testing for a familial disorder. Journal of Medical Genetics, 43(8), 665-670. https://doi.org/10.1136/jmg.2005.039172
  3. 3.Kuchenbaecker, K. B., Hopper, J. L., Barnes, D. R., Phillips, K. A., Mooij, T. M., Roos-Blom, M. J., ... & Olsson, H. (2017). Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers. JAMA, 317(23), 2402-2416. https://doi.org/10.1001/jama.2017.7112
  4. 4.Caswell-Jin, J. L., Zimmer, A. D., Stedden, W., Kingham, K. E., Zhou, A. Y., Kurian, A. W., & Harrington, C. (2019). Cascade genetic testing of relatives for hereditary breast and ovarian cancer: results of an online training course. Journal of Medical Genetics, 56(10), 668-673. https://doi.org/10.1136/jmedgenet-2018-105829
  5. 5.National Health and Medical Research Council. (2019). Clinical practice guidelines for the management of women with epithelial ovarian cancer. NHMRC. https://www.nhmrc.gov.au/about-us/publications/clinical-practice-guidelines-management-women-epithelial-ovarian-cancer
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