Evidence-Based Medicine

Research Appraisals

Evidence-based critical appraisals of the latest medical research, systematically evaluated using Oxford CEBM methodology.

Showing 3 appraisals

observationalEvidence: Insufficient
50CEBM

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

Empowerment gain and causal model construction: children and adults are sensitive to controllability and variability in their causal interventions

Learning about the causal structure of the world is a fundamental problem for human cognition. Causal models and especially causal learning have proved to be difficult for large pretrained models using standard techniques of deep learning. In contrast, cognitive scientists have applied advances in our formal understanding of causation in computer science, particularly within the causal Bayes net formalism, to understand human causal learning. In the very different tradition of reinforcement learning (RL), researchers have described an intrinsic reward signal called 'empowerment' which maximizes mutual information between actions and their outcomes. Empowerment may be an important bridge between classical Bayesian causal learning and RL and may help to characterize causal learning in humans and enable it in machines. If an agent learns an accurate causal world model, they will necessarily increase their empowerment, and increasing empowerment will lead to a more accurate causal world model. Empowerment may also explain distinctive features of children's causal learning, as well as providing a more tractable computational account of how that learning is possible. In an empirical study, we systematically test how children and adults use cues to empowerment to infer causal relations and design effective causal interventions. This article is part of the theme issue 'World models in natural and artificial intelligence'.

15 May 2026

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otherEvidence: Moderate
75CEBM

Developmental science

Making Machine Learning Accessible for Developmental Science: The Case of Automated Face Detection

The last decade has seen rapid advancements in machine learning, significantly transforming fields like cybersecurity and healthcare. Developmental science has been slower to adopt these technologies. Yet, machine learning holds immense potential to transform this field, enabling scalable and data-driven insights into developmental processes. Broader adoption is currently hindered by challenges in algorithm selection and technical implementation. We address these barriers by focusing on an area that has reached high sophistication from a machine learning perspective while also being of significant interest to developmental scientists: face detection. Face detection is crucial for analysing visual experiences through children's dynamic, first-person views. Automatising this process allows efficient handling of large egocentric datasets, enabling well-powered studies otherwise limited by labour-intensive manual annotation. Here, we systematically evaluated 13 state-of-the-art face detection algorithms (DeepFace library) using data from two increasingly common developmental methodologies involving children under 3 years of age: head-mounted eye-tracking in more structured settings (N = 20; n = 10 4-month-olds, n = 10 8-month-olds) and head-mounted cameras in naturalistic home environments (N = 10 18-29-month-olds). Benchmarking these algorithms against manual annotations revealed that YOLOv11Face (M) and RetinaFace consistently outperformed others in terms of precision and recall, exhibiting strong concordance with manual ratings, lower error, reduced systematic deviation and robust rank-order correlations with manual annotations. To facilitate broader adoption, we introduce an accessible face detection tool (TinyExplorer Detection App), promoting efficiency, scalability, and innovation in developmental science by widening access to machine learning.

5 May 2026

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otherEvidence: Strong
85CEBM

Behavior research methods

FaceTrack-AOI: An AI-driven tool for automated dynamic AOI placement and eye movement analysis in face perception studies

Face perception is fundamental to human social interaction, relying on the dynamic allocation of visual attention to facial features across natural variations in poses, expressions, lighting and context-critical factors for real-world face perception. While eye-tracking studies have advanced our understanding of this process, analyzing gaze data in naturalistic settings presents challenges due to the labor-intensive and often subjective process of manually defining areas of interest (AOI) in dynamic stimuli. We introduce FaceTrack-AOI, an open-source, artificial intelligence (AI)-driven tool that automates dynamic AOI construction using robust 68-point facial landmark detection. Featuring a user-friendly graphical interface, the tool allows researchers to define and export eye movement metrics without programming expertise. It supports both rectangular and polygon-based AOIs, with customizable buffers, blank zones, and hierarchical configurations, accommodating diverse theoretical and methodological needs. Validation on multi-ethnic naturalistic video frames, images from a standardized face dataset (Chinese Face and Body Dataset [CFBD]), and benchmarks against a published study revealed strong agreement with expert-defined manual AOIs, achieving a mean spatial overlap of 95.73%. A proof-of-concept validation confirmed high fixation capture: over 98.8% of dwell time was correctly directed toward key AOIs. In two experiments with infants (6-18 months) and adults viewing 28,800 dynamic video frames, and children (2-8 years), both neurotypical and with autism spectrum disorder (ASD), viewing 80 static faces, FaceTrack-AOI demonstrated enhanced sensitivity in detecting developmental and group differences in naturalistic face recognition. By integrating AI-powered tracking with an intuitive interface, FaceTrack-AOI streamlines gaze analysis for dynamic facial stimuli, offering researchers an efficient and scalable solution to advance face perception research in ecologically valid contexts.

26 Apr 2026

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