RecruitingNANCT07301307

The Use of the Hypotension Prediction Index (HPI) Combined With the Assisted Fluid Management (AFM) Software for Perioperative Hemodynamic Optimization in Patients Undergoing General Anesthesia.

Sponsor: National and Kapodistrian University of Athens

Trial Details

Condition	Intraoperative Hypotension
Intervention	Acumen IQ sensor with Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) software; Conventional Intraoperative Hemodynamic management
Phase	NA
Status	Recruiting
Participants	100
Est. Completion	1 Oct 2026
Last Updated	20 Apr 2026

Primary Outcome

Time-weighted average of intraoperative hypotension

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: * Age \> 18 years * Intraoperative monitoring \> 2 hours or general anesthesia \> 2 hours * Invasive arterial pressure monitoring * Target MAP ≥ 65 mm Hg intraoperatively * Written informed consent preoperatively * ASA Physical Status ≤ 4 Exclusion Criteria: * Target MAP other than 65 mm Hg * Severe preoperative hypotension (MAP \< 65 mm Hg) * Severe heart failure (e.g. LVEF \< 20%) * Emergency surgery

Trial Sites

Countries

Greece

View Registry Entry

Related Analysis

Phase IV Trial Opens: AI-Guided Hypotension Prediction vs Conventional Management in General Anaesthesia — What Anaesthetists Need to Know

New trial investigates whether predictive algorithms can prevent intraoperative hypotension before it occurs. Greek researchers are testing machine learning technology that analyses arterial waveforms to predict and prevent hypotensive episodes during surgery.

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