CompletedNANCT06813066

Simulating Psychotherapeutic Sessions With Generative Artificial Intelligence: A Proof-of-Concept Study of In Silico Psychotherapy Research

Sponsor: University Hospital, Basel, Switzerland

Trial Details

Condition	Mental Disorder
Intervention	High Levels of Common Therapeutic Factors; Low Levels of Common Therapeutic Factors; Standard motivational interviewing
Phase	NA
Status	Completed
Participants	520
Est. Completion	31 Aug 2025
Last Updated	22 May 2026

Primary Outcome

Simulation's Accuracy in generating Psychotherapeutic Dialogues

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: * Simulation of psychotherapy sessions of conversations between an adult person presenting with a mental or behavioral health problem and a psychotherapist using large language models and 8 real-world transcripts Exclusion Criteria: * Simulation protocols with severe simulation errors

Trial Sites

Countries

Switzerland

View Registry Entry

Related Analysis

Completed Swiss Study Tests AI Simulation of Psychotherapy Sessions — Implications for Mental Health Training and Research

Swiss researchers completed a groundbreaking study using large language models to simulate psychotherapy sessions, testing whether computational models can accurately replicate therapeutic dialogues. The proof-of-concept study analysed 520 simulated sessions, potentially revolutionising mental health training and research methodologies.

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