Randomized Trial Of A Digital Lifestyle Education Strategy In Patients With Heart Failure And Overweight Or Obesity: The ELITE-HFpEF Study
Sponsor: Maimónides Biomedical Research Institute of Córdoba
Trial Details
| Condition | Heart Failure and Preserved Ejection Fraction, Obesity & Overweight, Heart Failure |
| Intervention | Digital lifestyle education program; Usual Care |
| Phase | NA |
| Status | Not_yet_recruiting |
| Participants | 52 |
| Est. Completion | 31 Dec 2028 |
| Last Updated | 22 June 2026 |
Primary Outcome
Change in peak oxygen uptake (VO2max); Change in peak oxygen uptake (VO2max)
Eligibility Criteria
Inclusion Criteria
Inclusion Criteria: * Age over 18 years * Body mass index (BMI) over 27 kg/m² * Symptoms consistent with heart failure * Left ventricular ejection fraction (LVEF) of 50% or higher * Elevated NT-proBNP according to the European Society of Cardiology age-adjusted rule-in thresholds: 125 pg/mL or higher if under 50 years, 250 pg/mL or higher if 50 to 75 years, and 500 pg/mL or higher if 75 years or older * Echocardiographic abnormalities: left ventricular hypertrophy, left atrial enlargement, or diastolic dysfunction Exclusion Criteria: * Body mass index (BMI) over 40 kg/m² * Life expectancy of less than 1 year * Chronic kidney disease on renal replacement therapy * Moderate or greater valvular heart disease * Inability to exercise
Trial Sites
Countries
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