Coronary Computed Tomographic Angiography to Optimize Diagnostic Yield of Invasive Angiography for Low-risk Patients Screened With Artificial Intelligence

Inclusion Criteria

Patients are eligible to participate if they: 1) are ≥18 years of age; 2) are referred for non-urgent (elective) outpatient ICA; 3) have an indication for ICA that includes 'Rule out CAD', 'Cardiomyopathy', or 'Stable CAD'; and 4) are able to provide informed consent in English. Patients fulfilling any of the following criteria will be ineligible to participate: 1) prior high-quality coronary computed tomographic angiography (CCTA) within the last 5 years; 2) atrial fibrillation; 3) known severe renal dysfunction (GFR \<35); 4) planned non-coronary cardiac surgery; 5) any prior obstructive CAD, acute coronary syndrome, percutaneous coronary intervention, or coronary artery bypass graft; 6) known severe coronary artery calcification (calcium score \>250); or have a body mass index (BMI) exceeding 40.