ActiveNANCT05656560

Reducing High Risk Polypharmacy Using Behavioral Economics Through Electronic Health Records

Sponsor: Northwestern University

Trial Details

Condition	Polypharmacy
Intervention	Clinical decision support (CDS)-Commitment nudge; Clinician education; Clinical decision support (CDS)-Justification nudge
Phase	NA
Status	Active
Participants	786
Est. Completion	10 May 2026
Last Updated	26 May 2026

Primary Outcome

The percentage of HRPP with any (1 or more) of the 7 measures of high risk polypharmacy. (Composite measure)

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: * Northwestern Medicine or UPMC primary care clinic: Internal Medicine, Family Medicine, or General Practice or Geriatrics Exclusion Criteria: * None

Trial Sites

Countries

United States

View Registry Entry

Related Analysis

Pragmatic Trial Tests EHR Nudges to Reduce High-Risk Polypharmacy in Primary Care — Behavioral Economics Meets Clinical Decision Support

A pragmatic US trial tests whether EHR-based behavioral nudges can help primary care clinicians reduce high-risk polypharmacy in older adults. The study evaluates commitment and justification nudges integrated into clinical workflows, with particular focus on patients with dementia or cognitive impairment.

Read full article →

This content is for educational purposes for healthcare professionals only and does not constitute clinical advice. Clinical decisions should be based on individual patient assessment, current guidelines, and appropriate specialist consultation. Editorial Standards · Privacy Policy · Terms of Service