Identification of Risk Factors and Development of an Interpretable Machine Learning Model for Predicting Insulin Resistance in Patients With Psoriasis

Inclusion Criteria

Inclusion Criteria: * Adults aged 18 years or older * Diagnosed with psoriasis (including plaque psoriasis, pustular psoriasis, erythrodermic psoriasis, or other clinically recognized subtypes), according to established clinical diagnostic guidelines * Received medical care at Chinese PLA General Hospital (First Medical Center) or the collaborating center (Fourth Medical Center) during the study period * Availability of complete medical records, including demographic information, relevant clinical characteristics, and laboratory data required to assess insulin resistance Exclusion Criteria: * Previous or current diagnosis of diabetes mellitus * Presence of severe systemic diseases that may significantly affect glucose metabolism (such as malignant tumors, hyperthyroidism, or other serious endocrine disorders) * Current or recent use of systemic medications known to affect insulin sensitivity, including:Systemic corticosteroids,Glucose-lowering medications, or Other medications with known significant effects on insulin resistance * Pregnant or breastfeeding women * Medical records with missing key variables required for the assessment of insulin resistance or model development