RecruitingPHASE4NCT07362433

The BLAAAST Trial: Bangladesh Lung Auscultation AI for Antibiotic Stewardship Randomized Controlled Trial

Sponsor: Johns Hopkins University

Trial Details

ConditionRespiratory Infections in Children
InterventionAutomated digital stethoscope
PhasePHASE4
StatusRecruiting
Participants2,500
Est. Completion30 June 2029
Last Updated8 June 2026

Primary Outcome

Treatment failure

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: * 2 to 59 months of age (60 days to 59 months 29 days), * illness duration 14 days or less, * meeting non-severe pneumonia criteria, and * from the trial catchment areas. Exclusion Criteria: * prior participation, * age \<2 months or \>59 months, * illness duration \>14 days, * not meeting IMCI-defined non-severe pneumonia criteria, * oxygen saturation (SpO2) \<90%, * moderate or severe malnutrition, * known chronic disease, * history of prematurity, * one or more high risk clinical signs (any WHO-defined clinical danger sign and/or WHO-defined emergency sign), * known antibiotic exposure in the past 1 week, * non-respiratory illness requiring systemic antibiotic treatment according to IMCI guidelines.

Trial Sites

Countries

Bangladesh
View Registry Entry

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