The BLAAAST Trial: Bangladesh Lung Auscultation AI for Antibiotic Stewardship Randomized Controlled Trial
Sponsor: Johns Hopkins University
Trial Details
| Condition | Respiratory Infections in Children |
| Intervention | Automated digital stethoscope |
| Phase | PHASE4 |
| Status | Recruiting |
| Participants | 2,500 |
| Est. Completion | 30 June 2029 |
| Last Updated | 8 June 2026 |
Primary Outcome
Treatment failure
Eligibility Criteria
Inclusion Criteria
Inclusion Criteria: * 2 to 59 months of age (60 days to 59 months 29 days), * illness duration 14 days or less, * meeting non-severe pneumonia criteria, and * from the trial catchment areas. Exclusion Criteria: * prior participation, * age \<2 months or \>59 months, * illness duration \>14 days, * not meeting IMCI-defined non-severe pneumonia criteria, * oxygen saturation (SpO2) \<90%, * moderate or severe malnutrition, * known chronic disease, * history of prematurity, * one or more high risk clinical signs (any WHO-defined clinical danger sign and/or WHO-defined emergency sign), * known antibiotic exposure in the past 1 week, * non-respiratory illness requiring systemic antibiotic treatment according to IMCI guidelines.
Trial Sites
Countries
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