Exercogs®: Efficacy of a Multidomain Digital Therapeutic Solution for Preventing Cognitive Decline in Adults Aged ≥55 With Modifiable Risk Factors - Randomized Controlled Trial

Inclusion Criteria

Inclusion Criteria: * Age 55 years or older * Presence of ≥1 modifiable risk factor according to the Lancet Commission on Dementia Prevention, Intervention, and Care (2024): low education, untreated hearing or visual loss, hypertension, obesity, smoking, depression, physical inactivity, type 2 diabetes, social isolation, excessive alcohol consumption, history of head trauma, air pollution exposure, high LDL/dyslipidemia; additional social and structural determinants, including poverty, income inequality, wealth shocks, and HIV, that may also contribute to risk (Mostert et al., 2025); * Ability and willingness to participate in 60-minute sessions, three times per week, during the 24-week intervention period; * Ability to provide written informed consent, or, in cases of reduced decisional capacity, provision of consent by a legally authorized representative. Exclusion Criteria: * Clinical diagnosis of Alzheimer's disease or dementia; * Severe neurological disorder or unstable medical condition that may interfere with participation; * Sensory or language deficits that would prevent understanding of instructions or safe participation; * Current participation in another interventional study that may confound outcomes (e.g., cognitive training, physical exercise, or multidomain rehabilitation); * Previous experience with Exercogs®.