CompletedNCT07592039

Research on Intelligent Optimization of Ventilator Parameters for Intensive Care Patients Based on Multimodal Large Models

Sponsor: Wu Rongzhou

Trial Details

Condition	Acute Respiratory Distress Syndrome, Pneumonia in Children, Respiratory Failure (Pediatric Patients)
Status	Completed
Participants	2,000
Est. Completion	31 Dec 2025
Last Updated	18 May 2026

Primary Outcome

Number of ventilator-free days within 28 days

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: 1. PICU patients aged 1 month to 18 years. 2. Receiving invasive mechanical ventilation, expected to last ≥ 48 hours. 3. Informed consent signed prior to enrollment. Exclusion Criteria: 1. Expected survival \< 24 hours 2. Irreversible brain injury (GCS = 3 + absence of brainstem reflexes) 3. Severe congenital cardiopulmonary malformations affecting ventilation assessment 4. Pregnancy (must be ruled out in adolescent girls) 5. Currently participating in other ventilation intervention trials 6. Guardian refusal to participate

Trial Sites

Countries

China

View Registry Entry

Related Analysis

Completed Observational Study Examines AI-Assisted Ventilator Management in Pediatric ICU — Implications for Respiratory Care

A completed observational study of 2,000 pediatric ICU patients examined whether computational decision support could improve ventilator management outcomes. The research focused on ventilator-free days in children with respiratory failure, ARDS, and pneumonia.

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