Impact of Vital Pulp Therapy in Acute Irreversible Pulpitis With Incipient Apical Periodontitis Cases Diagnosed by the Aid of Artificial Intelligence: A Randomized Controlled Clinical Trial
Sponsor: Ain Shams University
Trial Details
| Condition | Symptomatic Irreversible Pulpitis |
| Intervention | Vital Pulp Therapy; Root Canal Treatment |
| Phase | NA |
| Status | Active |
| Participants | 34 |
| Est. Completion | 8 Apr 2026 |
| Last Updated | 24 Apr 2026 |
Primary Outcome
Pain Score
Eligibility Criteria
Inclusion Criteria
Inclusion Criteria: * Mandibular molars with with deep caries exposing the pulp and preoperative symptoms, such as spontaneous or referred pain. * Mandibular molars lacking noticeable radiolucency in the furcation or periapical areas. (Periapical Index scores of 1 and 2) * Patients aged 18-40 years with teeth diagnosed with acute irreversible pulpitis and symptomatic apical periodontitis. * Patients willing to provide written informed consent for participation in the study. * Restorable teeth and adequate periodontal support. Exclusion Criteria: * Teeth with prior endodontic treatment or history of trauma. * Teeth with internal or external resorption, prominent radiolucency at the periapical regions or furcation. (Periapical Index score of 3, 4 and 5) * Teeth that are not responsive to vitality tests. * Pregnant or lactating women due to potential risks associated with radiographic exposure. * Patients with systemic diseases (e.g., uncontrolled diabetes, immunosuppression) that may affect healing. * Teeth with advanced periodontal disease (e.g., mobility grade II or III, furcation involvement). * Patients unable to attend follow-up appointments for up to one year.
Trial Sites
Countries
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