ActiveNANCT07549620

Impact of Vital Pulp Therapy in Acute Irreversible Pulpitis With Incipient Apical Periodontitis Cases Diagnosed by the Aid of Artificial Intelligence: A Randomized Controlled Clinical Trial

Sponsor: Ain Shams University

Trial Details

ConditionSymptomatic Irreversible Pulpitis
InterventionVital Pulp Therapy; Root Canal Treatment
PhaseNA
StatusActive
Participants34
Est. Completion8 Apr 2026
Last Updated24 Apr 2026

Primary Outcome

Pain Score

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: * Mandibular molars with with deep caries exposing the pulp and preoperative symptoms, such as spontaneous or referred pain. * Mandibular molars lacking noticeable radiolucency in the furcation or periapical areas. (Periapical Index scores of 1 and 2) * Patients aged 18-40 years with teeth diagnosed with acute irreversible pulpitis and symptomatic apical periodontitis. * Patients willing to provide written informed consent for participation in the study. * Restorable teeth and adequate periodontal support. Exclusion Criteria: * Teeth with prior endodontic treatment or history of trauma. * Teeth with internal or external resorption, prominent radiolucency at the periapical regions or furcation. (Periapical Index score of 3, 4 and 5) * Teeth that are not responsive to vitality tests. * Pregnant or lactating women due to potential risks associated with radiographic exposure. * Patients with systemic diseases (e.g., uncontrolled diabetes, immunosuppression) that may affect healing. * Teeth with advanced periodontal disease (e.g., mobility grade II or III, furcation involvement). * Patients unable to attend follow-up appointments for up to one year.

Trial Sites

Countries

Egypt
View Registry Entry

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