Not_yet_recruitingNANCT07589062

HEAL MS: A Culturally Adapted Lifestyle Medicine Intervention Targeting Metabolic and Immune Dysregulation in Multiple Sclerosis Using Multi-Omics Profiling

Sponsor: New York University Abu Dhabi

Trial Details

Condition	Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis
Intervention	Multi-Domain Lifestyle Intervention
Phase	NA
Status	Not_yet_recruiting
Participants	30
Est. Completion	15 Nov 2027
Last Updated	15 May 2026

Primary Outcome

Recruitment Rate (Number of Participants Enrolled per Month); Retention Rate (Percentage of Participants Completing All Study Assessments); Exercise Adherence (Percentage of Completed Scheduled Exercise Sessions); Mobile Application Engagement (Average Daily Completion Rate of App-Based Logs); Acceptability of HEAL MS Intervention (Participant Satisfaction Score)

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: * Confirmed MS diagnosis (McDonald criteria) * EDSS score ≤ 6.5 (i.e., ambulatory with or without assistance) * Stable disease-modifying therapy for ≥ 3 months * Age 18-50 * Proficiency in English or Arabic * Clearance to participate in a structured exercise program * Ability to walk, sit and stand independently, and perform light-to-moderate movement patterns, even with modifications * Ability and digital literacy to interact with the bilingual HEAL MS mobile app and * Access to a computer for participation in online sessions Exclusion Criteria: * Significant cognitive impairment affecting app use and comprehension of the intervention * MS relapse within the past 3 months * Pregnancy or planned pregnancy * Unmanaged psychiatric disorders * Other immune-related or chronic inflammatory or metabolic diseases * Concurrent enrollment in another lifestyle intervention

Trial Sites

Countries

United Arab Emirates

View Registry Entry

Related Analysis

HEAL MS Trial: Novel Culturally-Adapted Lifestyle Intervention for Multiple Sclerosis — Multi-Omics Approach to Metabolic and Immune Dysregulation

New HEAL MS trial investigates culturally-adapted lifestyle medicine intervention for multiple sclerosis patients using multi-omics profiling. The 12-week program targets nutrition, exercise, sleep, and stress management through digital health platforms.

Read full article →

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