A Randomized, Multicenter, 16-week Study to Evaluate the Efficacy and Safety of Two Prescription Digital Therapeutics as an Adjunct to Standard-of-Care Antipsychotic Therapy in Adult and Late Adolescent Participants With Experiential Negative Symptoms of Schizophrenia
Sponsor: Click Therapeutics, Inc.
Trial Details
| Condition | Schizophrenia |
| Intervention | CT-155; Digital Control |
| Phase | PHASE3 |
| Status | Completed |
| Participants | 464 |
| Est. Completion | 20 June 2025 |
| Last Updated | 12 June 2026 |
Primary Outcome
Experiential negative symptoms
Eligibility Criteria
Inclusion Criteria
Inclusion Criteria: A participant will be eligible for entry into the study if all of the following criteria are met: 1. Has a primary diagnosis of schizophrenia. 2. Is on a stable dose of antipsychotic medication(s). 3. Has obtained an average score of ≥2 (moderate to severe) in at least two of the three CAINS-MAP domains (Social, Work, or Recreational). Exclusion Criteria: A participant will not be eligible for study entry if any of the following criteria are met: 1. Is currently treated with more than two antipsychotic medications (including more than two dosage forms). 2. Meets DSM-5, for diagnoses not under investigation. 3. Has participated in a CT-155 clinical study.
Trial Sites
Countries
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