ActiveNANCT05180760

Effectiveness of a Smartphone App in Promoting Weight Loss in Patients With Non-alcoholic Fatty Liver Disease: a Pilot Multi-centre Randomized Controlled Trial

Sponsor: The University of Hong Kong

Trial Details

Condition	Non-Alcoholic Fatty Liver Disease
Intervention	Smartphone app use; Standard of care
Phase	NA
Status	Active
Participants	260
Est. Completion	31 Dec 2025
Last Updated	1 May 2026

Primary Outcome

Change in body weight

Eligibility Criteria

Inclusion Criteria

Inclusion Criteria: * known NAFLD * able to read and understand Chinese * owns a compatible smartphone * without major cognitive impairment. Exclusion Criteria: * newly initiated on sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide 1 receptor agonists or thiazolidinediones or had recent dose adjustments (within 3 months) * patients with cirrhosis * patients who are pregnant * patients on special diet or with special dietary requirement (e.g. vegan, gluten free) * patients with heavy alcohol use (≥20 grams/ day for women or ≥30 grams/ day for men) * history of HCC or LT

Trial Sites

Countries

China

View Registry Entry

Related Analysis

Digital Health Trial: Smartphone App vs Standard Care for Weight Loss in NAFLD — Hong Kong Multicentre Study

Hong Kong researchers are testing whether a smartphone app can help NAFLD patients achieve clinically meaningful weight loss. This 260-participant trial addresses the urgent need for effective interventions in the world's most common liver disease.

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