Research Appraisals
Evidence-based critical appraisals of the latest medical research, systematically evaluated using Oxford CEBM methodology.
Showing 4 appraisals
European journal of psychotraumatology
Differential linguistic patterns across Rorschach, TAT, and SCT in individuals with PTSD
Background: While prior studies have examined linguistic markers of PTSD using everyday discourse or autobiographical narratives, comparative studies identifying specific markers across different projective personality tests remain limited.Objective: To investigate whether language features in projective personality tests differentiate individuals with PTSD from non-PTSD controls and assess their predictive value for symptom severity.Method: Verbatim transcripts from 283 participants (183 PTSD, 100 controls) across the Rorschach, TAT, and SCT were analysed using NLP across six categories: negative emotion, positive emotion, insight, causation, body-related, and self-focus. ANCOVAs with Bonferroni correction compared linguistic indicators between groups controlling for age and sex. Hierarchical regression analyses assessed predictive validity for symptom severity.Results: Following Bonferroni correction (α = .0028), four indicators showed significant group differences (ηp² = .036-.092): Rorschach Negative Emotion, SCT Positive Emotion, SCT Insight, and TAT Negative Emotion. In the PTSD group, TAT Negative Emotion was the strongest cross-symptom predictor of PTSD, depressive, and anxiety severity. Reduced Rorschach Body-related language and elevated SCT Insight were associated with greater symptom burden. TAT Positive Emotion negatively predicted symptom severity. In the non-PTSD group, SCT Self-Focus was the strongest predictor of PTSD-related severity, and SCT Positive Emotion negatively predicted anxiety. A sensitivity analysis revealed that SCT Positive Emotion and TAT Negative Emotion did not replicate under a more conservative Core Lexicon and should be treated as exploratory; only Rorschach Negative Emotion and SCT Insight were robust across lexicon configurations.Conclusions: Individuals meeting PTSD criteria showed reduced somatic language and elevated negative emotional expression, while self-referential processing and positive emotional expression emerged as salient markers in non-clinical individuals, though these differences should be interpreted cautiously given substantial demographic imbalances. These preliminary findings suggest that projective linguistic analysis may have potential as a supplementary approach in trauma-related research, pending external validation and replication in independent datasets. Language reveals trauma in distinct ways: People with post-traumatic stress show different language patterns than those without trauma-related disorders, and these patterns vary depending on the type of psychological test used.Projective tests offer supplementary linguistic insights: Responses to structurally distinct projective tests elicit different patterns of emotional, cognitive, and somatic language, providing supplementary perspectives on trauma-related psychological functioning that may not be fully captured by a single assessment paradigm.Language analysis supports clinical insight: Systematic analysis of word use helps identify subtle markers of symptom severity, suggesting potential utility as a supplementary research approach for understanding and assessing trauma-related psychological functioning.
27 July 2026
Read appraisal →European journal of psychotraumatology
Assessment of functional impairment related to post-traumatic stress in children and adolescents: a systematic review
Background: Post-traumatic stress disorder (PTSD) often impairs children's and adolescents' functioning across different life domains. Significant functional impairment is a diagnostic criterion for PTSD in both the DSM-5 and the ICD-11, but the methods in terms of domains covered and scoring rules to assess functional impairments are quite inconsistent.Objective: This systematic review evaluates instruments specifically designed to assess post-traumatic stress symptoms (PTSS), PTSS modules within diagnostic interviews, and generic functional impairment measures used to capture PTSS-related functional impairment in children and adolescents.Method: A systematic search was conducted across six databases for studies published between January 2010 and November 2025. Eligible papers included the development or psychometric evaluation of PTSS-specific measures, PTSS modules in diagnostic interview, and generic functional impairment measures validated in samples exposed to trauma or adverse childhood experiences. Data were extracted and categorized based on assessed content domains, scoring methods, and psychometric properties, with results stratified by age group (6 years and younger versus 7 years and older).Results: From 3519 records, 30 papers met the inclusion criteria. Thirteen PTSS-specific instruments, one diagnostic interview module, and one generic functional impairment measure were identified. Together, these instruments assessed 11 different life domains, although considerable variation existed in the domains covered across tools. Scoring methods also varied, with approximately half using dichotomous response formats and the remainder using multi-categorical scales. Psychometric properties of the functional impairment scales were reported in only 20.7% of publications.Conclusion: Current tools for assessing PTSS-related functional impairment in youth lack standardization. There is a critical need for well-validated instruments that comprehensively capture the presence and severity of PTSS-related functional impairment. This systematic review identified and evaluated 15 instruments, comprising PTSS-specific measures, diagnostic interview modules, and generic functional impairment tools, used to assess PTSS-related functional impairment in children and adolescents.The instruments collectively assessed 11 different life domains; however, substantial variability existed in the domains covered, and scoring methods ranged from dichotomous formats to Likert-type scales.Only 20.7% of papers reported psychometric properties for functional impairment items, highlighting the critical need for standardized, developmentally appropriate tools with robust validation in children and adolescents with potentially traumatic experiences.
8 July 2026
Read appraisal →Journal of the American Medical Informatics Association : JAMIA
TRUST: an large language model-based dialogue system for trauma understanding and structured assessments
OBJECTIVES: While large language models (LLMs) have been widely used to assist clinicians and support patients, no existing work has explored dialogue systems for standard diagnostic interviews and assessments. This study aims to bridge the gap in mental healthcare accessibility by developing an LLM-powered dialogue system that replicates clinician behavior. MATERIALS AND METHODS: We introduce TRUST, a framework of cooperative LLM modules capable of conducting formal diagnostic interviews and assessments for post-traumatic stress disorder (PTSD) following the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5). To guide the generation of appropriate clinical responses, we propose a Dialogue Acts schema specifically designed for clinical interviews. Additionally, we develop a patient simulation approach based on real-life interview transcripts to replace time-consuming and costly manual testing by clinicians. RESULTS: A comprehensive set of evaluation metrics is designed to assess the dialogue system from both the agent and patient simulation perspectives. Expert evaluations by conversation and clinical specialists show that TRUST performs comparably to real-life clinical interviews. DISCUSSION: Our system performs with clinical quality approaching that of human clinicians, with room for future enhancements in communication styles and response appropriateness. CONCLUSIONS: Our TRUST framework shows its potential to facilitate mental healthcare availability.
2 July 2026
Read appraisal →BMJ open
Feasibility and acceptability of therapist-guided, asynchronous, internet-delivered trauma-focused CBT for adolescents with PTSD: a single-group feasibility trial in Sweden
OBJECTIVES: Trauma-focused cognitive behavioural therapy (TF-CBT) is the established first-line treatment for paediatric post-traumatic stress disorder (PTSD), but access to evidence-based care remains limited. This study aimed to evaluate the feasibility and acceptability of a therapist-guided, 12 week, internet-delivered TF-CBT (iTF-CBT) programme for adolescents with PTSD and to explore preliminary changes in PTSD symptoms. DESIGN: Single-group feasibility trial. SETTING: Save the Children, Sweden. PARTICIPANTS: Twenty-two adolescents (13-17 years, 82% female) with primary PTSD. INTERVENTIONS: A 12 week, therapist-guided, asynchronous, internet-delivered TF-CBT comprising eight modules and parallel caregiver modules with joint adolescent-caregiver activities. OUTCOMES: Feasibility measures included recruitment pace, participant retention, treatment adherence (module completion) and therapist time. Acceptability was evaluated through satisfaction, credibility, negative effects and reported adverse events. Within-group changes in PTSD severity using independent evaluator-rated Clinician-Administered PTSD Scale (CAPS-CA-5) and the self-reported Child and Adolescent Trauma Screen 2 (CATS-2) were used as indicators of potential clinical change. Assessments occurred at baseline, during treatment, post-treatment and at 1 month follow-up (primary endpoint). RESULTS: Recruitment was completed after 7 months of active enrolment. Retention and adherence were high, satisfaction and credibility ratings were favourable, and no intervention-related serious adverse events occurred. Within-group improvements were observed at the primary endpoint, with large reductions on CAPS-CA-5 (Cohen's d=1.27) and CATS-2 (Cohen's d=1.51). At follow-up, 47.6% of participants no longer met criteria for PTSD. CONCLUSIONS: Therapist-guided iTF-CBT for adolescents with PTSD was safe, feasible, acceptable and associated with potentially meaningful symptom improvements. These findings support further evaluation in larger, controlled trials to determine efficacy, cost-effectiveness and long-term outcomes. TRIAL REGISTRATION NUMBER: NCT06185244.
30 May 2026
Read appraisal →