Research Appraisalobservational

Virtual vs In-Person Neurologic Ambulatory Care: A Case-Control Study of Subsequent Health Care Utilization

NeurologyHill, Chloé E, Lin, Chun Chieh, Harris, Alyssa et al.26 May 2026DOI

Clinical Snapshot

95CEBM
Evidence: Strongobservational

PICO Framework

P — PopulationAdults with new outpatient neurology visits at 3 academic medical centers (September 2020-December 2021)
I — InterventionVirtual neurology consultation
C — ComparatorIn-person neurology consultation
O — OutcomesSubsequent healthcare utilization: neurologic follow-up, ED visits, hospitalizations, and testing within 30-90 days to 1 year

Bottom Line

This large propensity-matched cohort study demonstrates that virtual new neurology consultations result in similar downstream healthcare utilization compared to in-person visits, with equivalent 90-day follow-up rates and comparable emergency department visits and hospitalizations. While some variation exists by neurologic condition—with dementia patients showing higher follow-up after in-person visits and Parkinson's/MS patients after virtual visits—the overall findings support the safety and effectiveness of virtual neurology consultations for appropriately selected new patients. These results provide reassurance for continued telehealth integration in neurologic care, though individual patient factors and specific neurologic presentations should guide modality selection.

Evidence: Strong

Key Findings

  • P Value: p = 0.18 for primary outcome

  • Effect Size: Minimal difference in healthcare utilization between modalities

  • Primary Outcome: 90-day neurology follow-up: 24.6% virtual vs 23.7% in-person

  • Nnt Or Sensitivity: Risk difference <1% for most outcomes, suggesting clinical equivalence

  • Confidence Interval: Not reported

Clinical Application

High feasibility for appropriately selected patients, with some conditions (dementia) potentially benefiting from in-person assessment Relevant to Australian telehealth expansion post-COVID, though Medicare Benefits Schedule telehealth items and specialist referral patterns may differ from US academic settings Adult patients requiring new neurology consultation across various neurologic conditions

Abstract

BACKGROUND AND OBJECTIVES: Implementation of telemedicine expanded options for outpatient neurology care. It remains uncertain which new neurology patients can be appropriately evaluated virtually. We compared subsequent health care utilization after virtual vs in-person new patient neurology visits across 3 academic medical centers. METHODS: We conducted a retrospective multicenter cohort study of adults with a new outpatient neurology visit from September 2020 through December 2021 using the Vizient Clinical Data Base and Clinical Practice Solutions Center databases. Virtual and in-person patients were matched 1:1 using propensity scores incorporating demographics, clinical characteristics, time period, and previous health care utilization. Outcomes were analyzed overall and stratified by neurologic chief complaint category and institution. We compared rates of subsequent neurologic clinic follow-up, emergency department (ED) visits, and hospitalizations after virtual and in-person encounters. Testing and all-cause ED visits/hospitalizations were also assessed. RESULTS: We identified 10,428 virtual and 36,767 in-person neurology new outpatient visits. After propensity score matching, 8,202 virtual visits were matched to 8,202 in-person visits. Neurology follow-up within 90 days did not differ between virtual and in-person visits (24.6% vs 23.7%, p = 0.18). Thirty-day neurology clinic follow-up was slightly lower after virtual visits, whereas follow-up at 6 months and 1 year was similar between groups. Neurologic ED visits and hospitalizations within 90 days were similar (0.9% vs 0.8%, p = 0.23 and 1.8% vs 1.7%, p = 0.47, respectively). All-cause ED visits and hospitalizations within 90 days were also comparable (1.8% vs 1.7%, p = 0.59 and 2.2% vs 1.8%, p = 0.13, respectively). Analyses by chief complaint found that 90-day follow-up was higher after in-person visits for dementia, whereas 30- and 90-day follow-up was higher after virtual visits for Parkinson disease and multiple sclerosis, and 90-day follow-up was higher after virtual visits for headache. Testing was more frequent after in-person visits for certain chief complaints. DISCUSSION: In this propensity score-matched multicenter cohort, new neurology patients seen virtually had similar downstream utilization as those seen in-person, including comparable 90-day follow-up and similar neurologic and all-cause ED visits and hospitalizations. Although follow-up varied modestly by chief complaint and testing was more frequent after some in-person visits, no major differences emerged overall.

References

  1. 1.Hill, C. E., Lin, C. C., Harris, A., Anderson-Benge, E., Esper, C. D., Nair, K. V., de Havenon, A., Callaghan, B. C., Busis, N. A., & Esper, G. J. (2026). Virtual vs In-Person Neurologic Ambulatory Care: A Case-Control Study of Subsequent Health Care Utilization. Neurology. https://doi.org/10.1212/WNL.0000000000214989
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