Research Appraisalobservational

Towards fair and trustworthy heart rate estimation from wrist-worn photoplethysmography: a multi-wavelength dataset and uncertainty-aware deep learning approach evaluated across skin tones, sexes, and motion conditions

Physiological measurementRay, Daniel, Collins, Tim, Ponnapalli, Prasad V S8 Apr 2026DOI

Clinical Snapshot

85CEBM
Evidence: Moderateobservational

PICO Framework

P — PopulationAdults with diverse skin tones and sexes wearing wrist-worn PPG devices during various activities
I — InterventionMulti-wavelength (blue, green, red, IR) PPG with uncertainty-aware deep learning neural network
C — ComparatorSingle-wavelength PPG systems and baseline neural networks without uncertainty quantification
O — OutcomesHeart rate estimation accuracy (MAE), fairness across demographic groups, uncertainty calibration metrics, and prediction reliability

Bottom Line

This technology validation study demonstrates that multi-wavelength photoplethysmography combined with uncertainty-aware deep learning can significantly improve fairness in heart rate estimation across different skin tones and sexes. The approach eliminated demographic disparities (reducing skin tone-related errors from 1.2 BPM to zero) while maintaining accuracy. For Australian clinicians, this represents an important advancement in wearable device reliability, particularly relevant given our diverse population and increasing reliance on consumer health technologies. The uncertainty quantification feature could help identify when readings are unreliable, supporting more informed clinical decision-making. However, real-world validation and comparison with clinical-grade monitoring remains needed before widespread clinical adoption. The findings support more equitable deployment of wearable heart rate monitoring technology.

Evidence: Moderate

Key Findings

  • P Value: Not reported in abstract

  • Effect Size: Elimination of demographic parity gaps (1.2 BPM to 0.0 BPM for skin tone differences)

  • Primary Outcome: Heart rate estimation accuracy measured by mean absolute error (MAE)

  • Nnt Or Sensitivity: Miscalibration area of 0.12 for concrete dropout method indicating good uncertainty calibration

  • Confidence Interval: Not reported in abstract

Clinical Application

High feasibility given widespread adoption of wrist-worn devices, though computational requirements may limit real-time implementation Highly relevant to Australian healthcare given TGA regulation of wearable medical devices and increasing use in telehealth and remote monitoring programs Adults using consumer wearable devices for heart rate monitoring, particularly relevant for diverse populations

Abstract

Objective.To improve fairness (reduced disparities across skin tones and sexes) and trust (well-calibrated uncertainty metrics that indicate unreliable predictions) in wrist-worn photoplethysmography (PPG) heart rate estimation. While PPG offers a convenient, low-cost method for continuous heart rate monitoring, accuracy is often degraded by motion artefacts and demographic variation.Approach.We collected a multi-wavelength (blue, green, red, IR) wrist-worn PPG dataset covering diverse activities, skin tones, and sexes, and developed a multi-branch PPG-accelerometer fusion convolutional neural network quantifying both aleatoric and epistemic uncertainty (the latter via Monte Carlo dropout, concrete dropout, and deep ensembles). We compared wavelength sets, quantified demographic effects, and applied uncertainty-aware post-processing to filter out high-uncertainty predictions. Evaluation used leave-one-subject-out cross validation across both the collected multi-wavelength dataset and five commonly used single-wavelength datasets.Main results.Multi-wavelength fusion improved accuracy under motion, with blue-green-red-IR achieving the lowest mean absolute error (MAE). Baseline error was higher for participants with darker skin tones and for females; uncertainty-guided rejection reduced MAE and effectively eliminated these gaps (reducing parity gaps from 1.2 BPM to 0.0 BPM for skin tone). Concrete dropout provided the best calibration-accuracy-efficiency trade-off, achieving the lowest average miscalibration area (MA=0.12) while maintaining competitive MAE.Significance.Combining calibrated uncertainty with group-aware evaluation yields a more fair and trustworthy wrist-worn PPG heart rate estimation pipeline, supporting responsible deployment in consumer and sports contexts and informing bias-aware clinical development.

References

  1. 1.Ray, D., Collins, T., & Ponnapalli, P. V. S. (2026). Towards fair and trustworthy heart rate estimation from wrist-worn photoplethysmography: a multi-wavelength dataset and uncertainty-aware deep learning approach evaluated across skin tones, sexes, and motion conditions. Physiological Measurement. https://doi.org/10.1088/1361-6579/ae56ae
Share:XLinkedIn

This content is for educational purposes for healthcare professionals only and does not constitute clinical advice. Clinical decisions should be based on individual patient assessment, current guidelines, and appropriate specialist consultation. Editorial Standards · Privacy Policy · Terms of Service