Research AppraisalRandomised Controlled Trial

The effects of electroacupuncture and the Otago Exercise Program in older adults with sarcopenia: A randomized controlled study

MedicineWu, Wenzhe, Cao, Yanfei, Zhang, Yiting et al.22 May 2026DOI

Clinical Snapshot

55CEBM
Evidence: WeakRandomised Controlled Trial

PICO Framework

P — Population120 older adults with sarcopenia (mean age not specified, both male and female)
I — InterventionElectroacupuncture at ST31, ST32, GB34, ST36 (30 minutes, 3 times/week) plus Otago Exercise Program (30 minutes, 5 times/week) for 12 weeks
C — ComparatorOtago Exercise Program alone (30 minutes, 5 times/week) for 12 weeks
O — OutcomesPrimary: appendicular skeletal muscle mass-height index (ASM/H²). Secondary: grip strength, 4-metre gait speed, 6-minute walk distance

Bottom Line

This study suggests that combining electroacupuncture with the Otago Exercise Program may provide additional benefits for muscle mass and function in older adults with sarcopenia compared to exercise alone. However, the study has significant methodological limitations including poor reporting of randomisation, lack of effect sizes and confidence intervals, and no safety data. While the Otago Exercise Program is well-established for falls prevention in Australian practice, the addition of electroacupuncture requires further high-quality research before routine clinical recommendation. The study provides preliminary evidence but falls short of the methodological rigor needed for definitive clinical guidance. Clinicians should continue to recommend evidence-based exercise interventions for sarcopenia while considering acupuncture as an adjunctive therapy only after discussing limited evidence and potential costs with patients.

Evidence: Weak

Key Findings

  • P Value: P < 0.05 for between-group differences at 12 weeks

  • Effect Size: Not reported

  • Primary Outcome: Significant between-group differences in ASM/H² at 12 weeks favouring EA + OEP group

  • Nnt Or Sensitivity: Not calculable due to insufficient data reporting

  • Confidence Interval: Not reported

Clinical Application

Moderate - requires access to qualified acupuncturists and exercise physiologists. OEP is home-based and feasible OEP is endorsed by Australian guidelines for falls prevention. Acupuncture available through some allied health providers but not routinely covered by Medicare for sarcopenia Community-dwelling older adults with diagnosed sarcopenia who can participate in exercise programs

Abstract

BACKGROUND: The aim of this study was to investigate the effects of a combination of electroacupuncture (EA) and the Otago Exercise Program (OEP) for sarcopenia in older individuals and provide treatment recommendations for this patient population. METHODS: In this assessor-blinded randomized controlled trial, 120 older patients with sarcopenia were randomly divided into an OEP group (n = 58) and an EA + OEP group (n = 62). The OEP group received OEP 5 times/week, with each session lasting 30 minutes, for a duration of 12 weeks. In addition to OEP treatment, the EA + OEP group was treated with EA at ST31, ST32, GB34 and ST36 for 30 minutes 3 times/week for 12 weeks. The appendicular skeletal muscle mass-height index (ASM/H2) was the primary outcome. The secondary outcomes included grip strength, 4-m gait speed and 6-min walk distance. Outcomes were measured before initiation and at 6 and 12 weeks after initiation. RESULTS: Significant differences in ASM/H2, grip strength, 4-m gait speed and 6-min walk distance were detected between the 2 groups at week 12, whereas no differences were detected at weeks 0 and 6. In the EA + OEP group, as the treatment time increased, ASM/H2, grip strength, 4-m gait speed and 6-min walk distance increased significantly. In the OEP group, as the treatment time increased, no significant difference was found in ASM/H2, whereas grip strength, 4-m gait speed and 6-min walk distance increased significantly (P < .05). CONCLUSION: In older patients with sarcopenia, EA + OEP was associated with increased skeletal muscle mass, but no such effect was found for OEP alone. Moreover, EA + OEP was superior to OEP alone in terms of improving muscle strength and walking ability. EA + OEP may be considered an effective treatment for sarcopenia in older adults.

References

  1. 1.Wu, W., Cao, Y., Zhang, Y., Pang, J., Hu, H., & Gao, H. (2026). The effects of electroacupuncture and the Otago Exercise Program in older adults with sarcopenia: A randomized controlled study. Medicine, 105(21), e49033. https://doi.org/10.1097/MD.0000000000049033
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