The clinical performance of CAD/CAM-fabricated hybrid ceramic restorations in cases with severe wear: A 3-year clinical trial
Clinical Snapshot
PICO Framework
| P — Population | 49 patients with severe tooth wear requiring prosthetic management |
| I — Intervention | CAD/CAM-fabricated hybrid ceramic restorations (116 restorations total) |
| C — Comparator | No control group - single-arm prospective cohort study |
| O — Outcomes | Clinical performance parameters (esthetic, functional, biological), restoration wear, patient satisfaction, complications, and 3-year survival rates |
Bottom Line
This 3-year prospective cohort study demonstrates that CAD/CAM hybrid ceramic restorations achieve 88% survival in patients with severe tooth wear, with acceptable complication rates. The most common issues were restoration dislodgement (5.2%) and marginal chipping (4.3%), which were clinically manageable. Progressive wear increased after 18 months but remained clinically acceptable. Patient satisfaction was high for chewing efficiency and aesthetics. While the single-arm design limits comparative assessment, these findings support hybrid ceramics as a viable option for complex wear cases. Clinicians should counsel patients about the 12% failure rate over three years and the need for ongoing maintenance. The study's single-centre design and lack of control group warrant cautious interpretation, but the systematic follow-up and objective measurement techniques strengthen the evidence base for this treatment approach.
Key Findings
P Value: Not reported for survival analysis
Effect Size: 88.0% survival rate at 36 months
Primary Outcome: 3-year survival rate of hybrid ceramic restorations
Nnt Or Sensitivity: Complication rates: 5.2% dislodgement, 4.3% marginal chipping, 3.4% extensive fracture requiring replacement
Confidence Interval: Not reported in abstract
Clinical Application
Requires CAD/CAM technology and expertise in digital dentistry, readily available in Australian specialist practice Relevant to Australian prosthodontic practice; hybrid ceramics increasingly used for complex rehabilitation cases. Consider PBS item numbers for complex prosthodontic procedures and specialist referral pathways Adult patients with severe tooth wear requiring extensive prosthetic rehabilitation
Abstract
PURPOSE: To evaluate the clinical use of CAD/CAM hybrid ceramics in patients with severe tooth wear. METHODS: Forty-nine patients with severe tooth wear underwent prosthetic management with 116 hybrid ceramic restorations. The restorations were evaluated at 1 week and at 3, 6, 12, 18, 24, 30, and 36 months after placement. The amount of wear on the restorations, antagonist teeth, and opposite teeth was compared using digital superimposition analysis. A questionnaire was used to evaluate participants' satisfaction with the restorations. Complications were recorded, and survival rates were estimated using Kaplan-Meier analysis. RESULTS: The clinical performance of the restorations was stable for esthetic, functional, and biological parameters up to 3 years, except for greater changes in "surface and margin staining" and "fracture and retention." There was no significant difference in the amount of progressive wear among the restorations, antagonist teeth, and opposite side teeth until 18 months; however, the wear on the restorations increased gradually up to 36 months. Higher scores and identical satisfaction results were obtained for the chewing efficiency and cleanability during the observation period. The most common complications were restoration dislodgement (5.2%) and partial marginal chipping (4.3%), which were clinically repaired. Four restorations (3.4%) were extensively fractured and replaced. The estimated survival rate of the hybrid ceramic restorations at 3 years was 88.0%. CONCLUSIONS: The clinical use of hybrid ceramic restorations in patients with severe tooth wear improved chewing efficiency and esthetics, provided adequate resistance for load-bearing, and delivered a stable treatment outcome after functional use.
References
- 1.Yang, T. C., Shen, C. M., Chen, H. C., & Tseng, C. C. (2026). The clinical performance of CAD/CAM-fabricated hybrid ceramic restorations in cases with severe wear: A 3-year clinical trial. Journal of Prosthodontic Research. https://doi.org/10.2186/jpr.JPR_D_24_00267
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