Research Appraisalobservational

Prevalence and determinants of inadequately controlled diabetes in Qatar's public primary care settings: A cross-sectional study

PloS oneAlnuaimi, Ahmed Sameer, Syed, Muslim Abbas, Syed, Mohamed AhmedDOI

Clinical Snapshot

80CEBM
Evidence: Moderateobservational

PICO Framework

P — Population84,512 adult individuals with type 2 diabetes mellitus managed in Qatar's public primary care settings over 5 years (2018-2022)
I — InterventionNot applicable (observational study)
C — ComparatorAdequately controlled diabetes (HbA1c <7%) versus inadequately controlled diabetes (HbA1c ≥7%)
O — OutcomesPrevalence of inadequately controlled T2DM and associated risk factors including age, sex, nationality, and comorbidities

Bottom Line

This large cross-sectional study of over 84,000 patients in Qatar's primary care system reveals that 53% of adults with type 2 diabetes have inadequate glycaemic control (HbA1c ≥7%), with rates remaining persistently high over five years. Males, individuals of South Asian ethnicity, and Qatari nationals were at highest risk of poor control. Importantly, while hypertension and dyslipidemia were the most common comorbidities, retinopathy emerged as the strongest predictor of inadequate control. The study's strength lies in its comprehensive population-based approach using electronic health records, though the cross-sectional design limits causal inferences. For Australian clinicians, these findings highlight the ongoing challenge of diabetes management in primary care and support the need for targeted interventions, particularly for high-risk demographic groups. The persistent high rates of inadequate control despite established care systems underscore the complexity of diabetes management and the importance of individualised, culturally appropriate care strategies.

Evidence: Moderate

Key Findings

  • P Value: Not reported in abstract

  • Effect Size: 53% prevalence of inadequate glycaemic control

  • Primary Outcome: 53% prevalence of inadequately controlled T2DM (HbA1c ≥7%) remained stable over the last three years

  • Nnt Or Sensitivity: Retinopathy identified as strongest predictor of inadequate control despite lower frequency than hypertension and dyslipidemia

  • Confidence Interval: Not reported in abstract

Clinical Application

Findings support feasibility of using electronic health records for diabetes surveillance and quality improvement initiatives in primary care Relevant to Australian primary care given similar diabetes management guidelines and HbA1c targets. Could inform targeted interventions for high-risk groups including culturally diverse populations. May support PBS diabetes medication reviews and RACGP diabetes management protocols Adults with type 2 diabetes in primary care settings, particularly relevant for multicultural populations with high diabetes prevalence

Abstract

BACKGROUND: The prevalence of type 2 diabetes mellitus (T2DM) is rapidly increasing worldwide, causing serious morbidity and mortality. Proper management and control of T2DM are essential in slowing and reducing complications. Measuring the adequacy of diabetic control, therefore is one of the ways of evaluating the success of health care system and the individuals in addressing disease morbidity and mortality. This study was proposed to assess the extent of uncontrolled T2DM in ambulatory adults managed in the public primary care settings of Qatar over five years. In addition, it aimed to predict the risk of uncontrolled disease based on age, sex, nationality and comorbidity. METHODS: A cross sectional review of Electronic Health Records of 84,512 adult individuals with T2DM having at least one HbA1c blood test result per year during the 5 years study period (1st January 2018, to 31st December 2022) was analyzed. The term "inadequately controlled" T2DM was used to define an individual with HbA1c measurements of 7% or higher. RESULTS: The yearly prevalence of inadequately controlled T2DM remained stable at a high rate (53%) during the last three years of observations. Aging increases the probability of having inadequately controlled T2DM, but this was attributed to comorbidities. Adjusting for those comorbidities will show that younger ages are the ones at higher risk of being uncontrolled. Additionally, the study reported that hypertension and dyslipidemia are the most frequently prevalent comorbidities, nevertheless retinopathy, although less frequent, was the most important predictor for inadequately controlled T2DM. CONCLUSIONS: The study highlights the significant healthcare challenge posed by T2DM in Qatar due to its high prevalence and associated complications. Males, South Asian ethnic background and Qatari locals have the highest probability of being inadequately controlled. Overall, the study emphasizes the need for targeted interventions to address the challenges of controlling diabetes, particularly among high-risk groups identified in the study.

References

  1. 1.Alnuaimi, A. S., Syed, M. A., & Syed, M. A. (2026). Prevalence and determinants of inadequately controlled diabetes in Qatar's public primary care settings: A cross-sectional study. PLoS One. https://doi.org/10.1371/journal.pone.0346266
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