Research Appraisalother

MICCAI STS 2024 challenge: Semi-supervised instance-level tooth segmentation in panoramic X-ray and CBCT images

Medical image analysisWang, Yaqi, Li, Zhi, Wu, Chengyu et al.1 May 2026DOI

Clinical Snapshot

85CEBM
Evidence: Moderateother

PICO Framework

P — PopulationDental imaging datasets comprising 2380 OPG images and 330 CBCT scans with instance-level FDI annotations
I — InterventionSemi-supervised learning (SSL) methods for automated tooth segmentation
C — ComparatorFully-supervised nnU-Net baseline trained only on labeled data
O — OutcomesInstance Affinity (IA) score for 2D OPG and Instance Dice score for 3D CBCT segmentation performance

Bottom Line

This large-scale challenge study demonstrates that semi-supervised learning methods can significantly improve automated tooth segmentation in dental imaging when labeled data is scarce. The winning approaches achieved remarkable performance gains over traditional fully-supervised methods, with improvements of 44 and 61 percentage points for OPG and CBCT respectively. The most effective methods combined foundational models like SAM with multi-stage refinement pipelines. For Australian dental practitioners, this research suggests that automated tooth segmentation tools could become more accessible and accurate, potentially reducing the time and expertise required for detailed dental image analysis. However, clinical validation studies are needed before implementation in practice. The open-source availability of both datasets and code enhances reproducibility and future development of these technologies.

Evidence: Moderate

Key Findings

  • P Value: Not reported in abstract

  • Effect Size: 44 percentage point improvement in OPG Instance Affinity score; 61 percentage point improvement in CBCT Instance Dice score

  • Primary Outcome: Semi-supervised learning performance compared to fully-supervised baseline

  • Nnt Or Sensitivity: Instance Affinity and Instance Dice scores as primary performance metrics

  • Confidence Interval: Not reported in abstract

Clinical Application

High feasibility given widespread use of these imaging modalities in dental practice Highly relevant to Australian dental practice where OPG and CBCT are standard imaging modalities covered under various dental insurance schemes Dental practitioners using OPG and CBCT imaging for diagnosis and treatment planning

Abstract

Orthopantomogram (OPGs) and Cone-Beam Computed Tomography (CBCT) are vital for dentistry, but creating large datasets for automated tooth segmentation is hindered by the labor-intensive process of manual instance-level annotation. This research aimed to benchmark and advance semi-supervised learning (SSL) as a solution for this data scarcity problem. We organized the 2nd Semi-supervised Teeth Segmentation (STS 2024) Challenge at MICCAI 2024. We provided a large-scale dataset comprising over 90,000 2D images and 3D axial slices, which includes 2380 OPG images and 330 CBCT scans, all featuring detailed instance-level FDI annotations on part of the data. The challenge attracted 114 (OPG) and 106 (CBCT) registered teams. To ensure algorithmic excellence and full transparency, we rigorously evaluated the valid, open-source submissions from the top 10 (OPG) and top 5 (CBCT) teams, respectively. All successful submissions were deep learning-based SSL methods. The winning semi-supervised models demonstrated impressive performance gains over a fully-supervised nnU-Net baseline trained only on the labeled data. For the 2D OPG track, the top method improved the Instance Affinity (IA) score by over 44 percentage points. For the 3D CBCT track, the winning approach boosted the Instance Dice score by 61 percentage points. This challenge demonstrates the potential benefit benefit of SSL for complex, instance-level medical image segmentation tasks where labeled data is scarce. The most effective approaches consistently leveraged hybrid semi-supervised frameworks that combined knowledge from foundational models like SAM with multi-stage, coarse-to-fine refinement pipelines. Both the challenge dataset and the participants' submitted code have been made publicly available on GitHub (https://github.com/ricoleehduu/STS-Challenge-2024), ensuring transparency and reproducibility.

References

  1. 1.Wang, Y., Li, Z., Wu, C., Liu, J., Zhang, Y., Ni, J., Luo, Q., Chen, J., Zhang, H., Liu, J., Han, C., Fu, K., Ji, C., Cai, X., Hao, J., Zheng, Z., Xu, S., Chen, J., Yu, X., Zhang, Q., Qian, D., Wang, S., & Zhou, H. (2026). MICCAI STS 2024 challenge: Semi-supervised instance-level tooth segmentation in panoramic X-ray and CBCT images. Medical Image Analysis, 103986. https://doi.org/10.1016/j.media.2026.103986
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