Research Appraisalother

Mapping research fronts of reproductive medicine using the NHANES database: A bibliometric and thematic analysis

African journal of reproductive healthYang, Jie, Liao, Jun, Gao, Yan et al.14 Apr 2026DOI

Clinical Snapshot

75CEBM
Evidence: Moderateother

PICO Framework

P — PopulationReproductive medicine research literature (1,026 highly-cited papers and 232 NHANES-based studies)
I — InterventionBibliometric analysis using bibliometrix and VOSviewer tools
C — ComparatorNot applicable (descriptive bibliometric study)
O — OutcomesResearch trends, collaboration patterns, knowledge gaps, and future research directions in reproductive medicine

Bottom Line

This bibliometric analysis maps research trends in reproductive medicine, particularly studies using the NHANES database. While the methodology appears sound using established bibliometric tools, the abstract lacks specific quantitative findings and detailed selection criteria. The study identifies knowledge gaps and future research directions in reproductive health, which could inform Australian research priorities and funding decisions. However, the clinical impact depends on the quality of the full analysis and specific recommendations provided. The work appears valuable for research planning but requires careful interpretation given potential bibliometric biases and the preliminary nature of findings presented in the abstract.

Evidence: Moderate

Key Findings

  • Effect Size: Not applicable (descriptive study)

  • Primary Outcome: Identification of research trends and knowledge gaps in reproductive medicine using NHANES data

  • Nnt Or Sensitivity: Analysis of 1,026 highly-cited papers and 232 NHANES-based studies

  • Confidence Interval: Not reported

Clinical Application

High - provides research direction guidance without direct patient intervention Relevant for Australian reproductive health research priorities, NHMRC funding decisions, and integration with Australian longitudinal health studies Reproductive health researchers, clinicians, and policymakers globally

Abstract

Reproductive health, infertility, and perinatal diseases significantly challenge human health development and continuity, requiring multidisciplinary approaches for enhanced academic understanding and practical solutions. This study used bibliometric analysis to examine related articles in the web of science (WoS) database, employing tools including bibliometrix and VOSviewer for systematic literature analysis. To capture the broader context of high-impact research, we first analyzed 1,026 highly-cited and hot papers in reproductive medicine, which revealed evolving thematic trends and global collaboration patterns. Then we examined 232 literatures using NHANES datasets for reproductive health research to identify research gaps and opportunities for further research in this field. The analysis revealed key trends, areas of concentration, and potential knowledge gaps in the literature, while the thematic analysis of reproductive health studies utilizing the NHANES database further underscored the wealth of data amenable to multidisciplinary investigation. Future research directions to explore new dimensions of reproductive health, improving health policies and clinical practices in this field using NHANES database are also suggested. The study concludes that multidisciplinary research using comprehensive datasets like NHANES is crucial for advancing understanding of reproductive health, infertility, and perinatal outcomes. La santé reproductive, l'infertilité et les maladies périnatales constituent un défi majeur pour le développement et la continuité de la santé humaine, nécessitant des approches multidisciplinaires afin d'améliorer la compréhension académique et de proposer des solutions pratiques. Cette étude a utilisé une analyse bibliométrique pour examiner les articles pertinents dans la base de données WoS, en employant des outils tels que Bibliometrix et VOSviewer pour une analyse systématique de la littérature. Afin de saisir le contexte plus large de la recherche à fort impact, nous avons d'abord analysé 1 026 articles hautement cités et à tendance chaude en médecine reproductive, ce qui a révélé les tendances thématiques évolutives et les modèles de collaboration internationale. Nous avons ensuite examiné 232 publications utilisant les jeux de données NHANES pour la recherche sur la santé reproductive, afin d'identifier les lacunes de recherche et les opportunités pour de futures études dans ce domaine. L'analyse a mis en évidence les tendances clés, les domaines de concentration et les lacunes de connaissances potentielles dans la littérature, tandis que l'analyse thématique des études sur la santé reproductive utilisant les jeux de données NHANES a en outre souligné la richesse des données susceptibles d'être étudiées de manière multidisciplinaire. Les orientations futures de la recherche visant à explorer de nouvelles dimensions de la santé reproductive, à améliorer les politiques sanitaires et les pratiques cliniques dans ce domaine à l'aide des jeux de données NHANES sont également proposées. L'étude conclut que la recherche multidisciplinaire utilisant des jeux de données complets tels que NHANES est cruciale pour faire progresser la compréhension de la santé reproductive, de l'infertilité et des issues périnatales.

References

  1. 1.Yang, J., Liao, J., Gao, Y., Gu, Y., Chen, Y. X., Zhao, L. Y., Yan, Q. Y., & Li, H. M. (2026). Mapping research fronts of reproductive medicine using the NHANES database: A bibliometric and thematic analysis. African Journal of Reproductive Health, 30(6). https://doi.org/10.29063/ajrh2026/v30i6.7
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