Research AppraisalRandomised Controlled Trial

Impact of Instagram and TikTok influencer marketing on perceptions of e-cigarettes and perceptions of influencers in young adults: a randomised survey-based experiment

Tobacco controlVassey, Julia, Vogel, Erin A, Unger, Jennifer B et al.7 May 2026DOI

Clinical Snapshot

65CEBM
Evidence: ModerateRandomised Controlled Trial

PICO Framework

P — PopulationCalifornia young adults aged 18-26 years (N=1494, mean age 23, 63% female, 51% Hispanic)
I — InterventionExposure to 10 Instagram and TikTok videos featuring influencers promoting e-cigarettes alongside healthy lifestyle activities
C — ComparatorExposure to 10 videos featuring healthy lifestyle activities alone (without e-cigarette promotion)
O — OutcomesPrimary: harm perceptions of e-cigarettes and susceptibility to e-cigarette use among never-users. Secondary: perceived influencer credibility

Bottom Line

This randomised trial of 1494 California young adults found that exposure to social media influencers promoting e-cigarettes alongside healthy lifestyle content increased susceptibility to e-cigarette use and decreased harm perceptions compared to healthy lifestyle content alone. The effects were modest (ORs 1.12-1.22) but statistically significant, and importantly, only occurred when participants perceived influencers as credible. While the study has limitations including lack of blinding and short-term outcomes, it provides valuable evidence for public health policy regarding social media marketing of e-cigarettes. The findings suggest that interventions targeting influencer credibility assessment and social media literacy could help mitigate harmful effects of e-cigarette marketing among young adults. Australian clinicians should be aware of these influences when counselling young patients about e-cigarette risks and consider discussing social media influences on health perceptions.

Evidence: Moderate

Key Findings

  • P Value: Not explicitly reported but CIs exclude null value

  • Effect Size: Small to moderate effect sizes with ORs of 1.12 and 1.22

  • Primary Outcome: Experimental group showed lower harm perceptions (AOR 1.12) and higher susceptibility to e-cigarette use (AOR 1.22) compared to control

  • Nnt Or Sensitivity: Effects only observed when influencers perceived as credible, not when perceived as non-credible

  • Confidence Interval: 95% CI 1.03-1.21 for harm perceptions; 95% CI 1.11-1.34 for susceptibility

Clinical Application

Findings support public health interventions targeting social media literacy and influencer credibility assessment Relevant to Australian tobacco control efforts and TGA e-cigarette regulations; supports educational campaigns about social media influence on health behaviours Young adults aged 18-26 who use Instagram and TikTok, particularly those who have never used e-cigarettes

Abstract

BACKGROUND: Pairing e-cigarettes with healthy lifestyle contexts in influencers' promotional social media posts may increase e-cigarette use risk among young adults. This study examined the effects of e-cigarette and healthy lifestyle content on young adults' perceptions of influencer credibility, harm perceptions of, and susceptibility to use, e-cigarettes. METHODS: In this survey-based online, repeated-measures experiment (2023), California young adults (N=1494, Mage=23 (SD=1.8); 63% female, 51% Hispanic) were randomly shown 10 (total) Instagram and TikTok videos, featuring influencers promoting e-cigarettes alongside healthy lifestyle activities (experimental group), or a healthy lifestyle activity alone (control). After watching each video, participants rated perceived influencer credibility (eg, honesty). After watching all videos, harm perceptions of e-cigarettes were assessed among all participants and susceptibility to e-cigarette use was assessed among e-cigarette never-users. Harm perceptions and susceptibility outcomes were compared between groups (experimental vs control) and between participants who perceived influencers as credible versus non-credible, using binomial generalised linear mixed effects models. RESULTS: Participants in the experimental group were more likely to report lower harm perceptions (adjusted OR (AOR) 1.12; 95% CI 1.03; 1.21) and higher susceptibility to e-cigarette use (AOR 1.22, 95% CI 1.11; 1.34), than participants in the control condition. Similar results were found when influencers were perceived as credible, but not when they were perceived as non-credible. CONCLUSIONS: Social media influencers' posts promoting e-cigarette use along with healthy activities may contribute to young adult e-cigarette use. Decreasing perceived credibility of influencers could decrease the negative effects of their promotional posts. TRIAL REGISTRATION NUMBER: NCT06433466.

References

  1. 1.Vassey, J., Vogel, E. A., Unger, J. B., Cho, J., Bae, D., Donaldson, S. I., & Allem, J. P. (2024). Impact of Instagram and TikTok influencer marketing on perceptions of e-cigarettes and perceptions of influencers in young adults: a randomised survey-based experiment. Tobacco Control. https://doi.org/10.2196/42441
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