Fast occupational upper-limb radiation dose prediction using machine learning and Monte Carlo simulation

Clinical Snapshot

Key Findings

• P Value: Not applicable for validation study

• Effect Size: 3.69% average relative error

• Primary Outcome: Machine learning ensemble model accuracy for upper-limb radiation dose prediction

• Nnt Or Sensitivity: Computational speed: ~10 milliseconds per prediction vs hours for full Monte Carlo simulation

• Confidence Interval: Not explicitly reported

Clinical Application

High feasibility with existing computational infrastructure; requires integration with procedure planning systems Relevant to Australian radiation protection standards (ACPSEM, ARPANSA guidelines); could enhance compliance with occupational dose monitoring requirements Interventional radiologists, cardiologists, and other healthcare professionals performing image-guided procedures

Abstract

Interventional procedures expose physicians to scattered radiation, particularly to their upper extremities, posing occupational health risks. Existing extremity dosimeters such as thermoluminescents, optically stimulated luminescence rings and active personal dosimeters provide limited spatial information, exhibit angular and energy dependence and offer little or no real-time feedback. This study develops machine learning (ML) models to estimate radiation dose values at discrete upper-limb locations using Monte Carlo (MC)-derived data and procedure-specific parameters. A dataset of 10 000 MC dose maps was generated under varied clinical and geometric conditions. After log-transformation and normalisation, several ML models, including deep neural networks and tree-based regressor, were trained and assessed using five-fold cross-validation. Mean absolute error and relative error (RE) were evaluated on the original dose scale, and an ensemble of the three best-performing models was constructed to improve robustness. The ensemble consistently outperformed individual models, achieving an average RE of 3.69% and demonstrating stable performance across anatomical regions and dose levels. Highest accuracy was obtained for standard beam geometries, whereas larger discrepancies occurred in extreme configurations with steep dose gradients. Predicted dose patterns were consistent with the expected distributions across the upper-limb regions. The findings demonstrate the feasibility of ML-based extremity dose estimation in interventional environments. The proposed ensemble provides a rapid (around 10 ms), scalable alternative to full MC simulations, enabling near real-time predictions of upper-limb occupational dose and supporting optimisation of radiation protection practices in image-guided procedures.

References

1. 1.Harb, H., Taguelmimt, K., Benoit, D., Pham, C. H., Nasr, B., & Bert, J. (2026). Fast occupational upper-limb radiation dose prediction using machine learning and Monte Carlo simulation. Journal of Radiological Protection, Article ae63da. https://doi.org/10.1088/1361-6498/ae63da