Evaluation of equity in quality improvement for multiarterial grafting in females and patients with low socioeconomic status: retrospective analysis of a statewide collaborative database
Clinical Snapshot
PICO Framework
| P — Population | Patients undergoing first-time, isolated CABG receiving at least two bypass grafts from 2011-2022 in Michigan (n=40,322) |
| I — Intervention | Quality improvement efforts to increase multiarterial grafting |
| C — Comparator | Comparison between females vs males, and high vs low socioeconomic status (DCI quartiles) |
| O — Outcomes | Rate of multiarterial grafting and equity in its distribution across demographic groups |
Bottom Line
This large retrospective cohort study of 40,322 CABG patients demonstrates significant and persistent disparities in multiarterial grafting despite overall quality improvement efforts. Females were 49% less likely and patients from socioeconomically disadvantaged areas were 65% less likely to receive multiarterial grafting per 10-point DCI increase. These disparities remained unchanged over the 12-year study period, indicating that quality improvement initiatives may inadvertently widen healthcare gaps if equity is not explicitly addressed. The findings highlight the critical need for equity-focused quality metrics and targeted interventions to ensure that advances in surgical care benefit all patient populations equally. For Australian cardiac surgery programs, this study provides compelling evidence to incorporate demographic stratification into quality improvement frameworks and consider socioeconomic factors when evaluating surgical outcomes and access to optimal care.
Key Findings
P Value: p<0.001 for both sex and socioeconomic disparities
Effect Size: Females: OR 0.51 (95% CI 0.45-0.58); High vs low DCI: OR 0.35 per 10-point increase (95% CI 0.24-0.51)
Primary Outcome: Rate of multiarterial grafting: 15% overall, 10% in females vs 17% in males
Nnt Or Sensitivity: Absolute difference: 7% lower multiarterial grafting rate in females, 4% lower in highest vs lowest DCI quartile
Confidence Interval: 95% CI 0.45-0.58 for sex disparity, 95% CI 0.24-0.51 for socioeconomic disparity
Clinical Application
Requires systematic tracking of demographic data and surgical outcomes with equity-focused quality metrics Relevant to Australian cardiac surgery programs; SEIFA could substitute for DCI. Applicable to ANZSCTS quality initiatives and aligns with ACSQHC equity frameworks Patients undergoing CABG in health systems with quality improvement initiatives
Abstract
OBJECTIVES: Quality collaboratives improve quality of care at the hospital and collaborative levels, but less is understood about how such efforts affect patient-level disparities. This study evaluated how a quality improvement (QI) effort (increasing multiarterial grafting during coronary artery bypass grafting (CABG)) translated into populations which historically receive lower-quality care (females and patients of low socioeconomic status). DESIGN: Retrospective cohort study. SETTING: All non-federal hospitals in the state of Michigan that perform cardiac surgery and participate in a statewide collaborative database (n=33). PARTICIPANTS: Patients undergoing first-time, isolated CABG receiving at least two bypass grafts from 2011 to 2022 were identified. PRIMARY ENDPOINTS: Association of sex and socioeconomic status with multiarterial grafting was evaluated across the study period. The distressed community index (DCI), a socioeconomic ranking (0-not distressed, 100-severely distressed), was matched to the patient's zip code. Hierarchical regression modelling was performed to associate DCI and sex with multiarterial grafting, incorporating patient factors and hospital and surgeon effects. A sex-surgery year and DCI-surgery year interaction term was performed to assess the change in the rate of multiarterial grafting. RESULTS: A total of 40 322 patients underwent CABG at 33 centres with a median age of 66 years and 24% were female. The rate of multiarterial grafting was 15%, although lower among females (10% vs 17%) and the highest (vs lowest) DCI quartile (14% vs 18%). After risk adjustment, females were less likely to receive multiarterial grafting (ORadj 0.51 (95% CI 0.45 to 0.58), p<0.001). Patients living in zip codes with a higher DCI had lower adjusted odds of receiving multiarterial grafting (ORadj 0.35 per 10-point increase (95% CI 0.24 to 0.51), p<0.001), a finding that was independent of study time (sex-year and DCI-year interaction terms p>0.05). CONCLUSIONS: Despite a large overall increase in multiarterial grafting due to QI efforts, females and patients with low socioeconomic status had lower rates of multiarterial grafting. QI efforts should be evaluated both overall and among patients who historically receive lower quality care to improve quality and equity.
References
- 1.Wagner, C., Theurer, P. F., Clark, M., He, C., Braun, T., Azoury, F., Qandeel, H. G., Magouliotis, D. E., Martin, J., Pruitt, A., Topcu, A. C., Ailawadi, G., Likosky, D. S., Thompson, M. P., Pagani, F. D., & Hawkins, R. B. (2026). Evaluation of equity in quality improvement for multiarterial grafting in females and patients with low socioeconomic status: retrospective analysis of a statewide collaborative database. BMJ Open. https://doi.org/10.1136/bmjopen-2025-103070
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