Research Appraisalobservational

Evaluating GPT-4 Performance on Plastic Surgery Oral Examination Vignettes: A Quantitative and Qualitative Analysis

Annals of plastic surgerySalvato, Jason S, Salvato, Jordan C, Byrnes, Yasmeen M et al.1 May 2026DOI

Clinical Snapshot

75CEBM
Evidence: Moderateobservational

PICO Framework

P — PopulationTwelve clinical vignettes representing American Board of Plastic Surgery oral examination scenarios across aesthetic, reconstructive, hand, craniofacial, pediatric, and trauma surgery
I — InterventionGPT-4 artificial intelligence system responses to clinical vignettes
C — ComparatorBoard-certified plastic surgeon expert assessment using structured scoring rubric
O — OutcomesPerformance scores across six clinical domains (Case Introduction, Diagnosis, Treatment Planning, Patient Counseling, Operative Steps, Complication Management) on 0-4 scale

Bottom Line

This validation study demonstrates that GPT-4 achieves board-level performance on structured plastic surgery clinical vignettes, with passing rates exceeding 80% across most clinical domains. The AI system performed best in diagnosis and complication management but struggled with case introductions. Strong interrater reliability (κ = 0.70-0.89) supports the robustness of the assessment framework. However, the study's small sample size and lack of comparison with human trainees limit generalizability. While promising as an educational adjunct for board preparation, the technology requires specialty-specific optimization and cannot replace clinical judgment in complex, dynamic surgical scenarios. Australian plastic surgery training programs could consider incorporating such tools for structured learning, but must emphasize the limitations in real-world clinical decision-making.

Evidence: Moderate

Key Findings

  • P Value: Not reported

  • Effect Size: Mean domain scores ranging from 2.3 to 3.7 on 0-4 scale

  • Primary Outcome: Overall passing rates of 91.7% (rater 1) and 83.3% (rater 2) across clinical domains

  • Nnt Or Sensitivity: Highest performance in Diagnosis (84.4%) and Complication Handling (82.3%); lowest in Case Introductions (62.5%)

  • Confidence Interval: Not reported

Clinical Application

High feasibility given widespread availability of GPT-4 technology and structured assessment frameworks Relevant to RACS plastic surgery training programs and continuing professional development requirements under AHPRA registration Plastic surgery trainees preparing for board examinations and continuing medical education

Abstract

BACKGROUND: The use of artificial intelligence (AI) in medicine is rapidly evolving. However, its role in plastic and reconstructive surgery remains underexplored. Plastic surgery requires nuanced, dynamic decision making, and individualized care, making AI integration challenging. This study evaluates GPT-4's ability to respond to American Board of Plastic Surgery (ABPS) Oral Board-style clinical vignettes and assesses its potential as a decision making and educational adjunct. METHODS: Twelve clinical vignettes spanning aesthetic, reconstructive, hand, craniofacial, pediatric, and trauma surgery were input into GPT-4. Each response was scored by 2 board-certified plastic surgeons across 6 clinical domains: Case Introduction, Diagnosis, Treatment Planning, Patient Counseling, Operative Steps, and Complication Management. Domains were scored on a 0-4 scale; scores <2 were considered failing. Interrater reliability was assessed via weighted κ . A structured qualitative interview was conducted. RESULTS: GPT-4 achieved mean domain scores ranging from 2.3 to 3.7 across vignettes, with passing rates of 91.7% (rater 1) and 83.3% (rater 2). The highest-performing domains were Diagnosis (84.4%) and Complication Handling (82.3%), and the lowest-performing domains were seen in Case Introductions (62.5%). Interrater agreement was strong across domains ( κ = 0.70-0.89). Qualitative findings emphasized GPT-4's accuracy in guideline-based cases, limitations in trauma triage, and potential as an educational resource. CONCLUSION: GPT-4 demonstrates concordance with board-level clinical reasoning in structured plastic surgery scenarios. However, limitations in heuristic judgment and real-time adaptability underscore the need for optimization with specialty-specific training datasets and performance rubrics. With appropriate curation, GPT-4 could serve as a valuable supplement in surgical education and oral board preparation.

References

  1. 1.Salvato, J. S., Salvato, J. C., Byrnes, Y. M., Wang, S. K., Kauffman, C. A., & Devitt, S. M. (2026). Evaluating GPT-4 Performance on Plastic Surgery Oral Examination Vignettes: A Quantitative and Qualitative Analysis. Annals of Plastic Surgery. https://doi.org/10.1101/2024.05.31.24308044
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