Research AppraisalRandomised Controlled Trial

Digital Twins for Decision Making: Combining Ambulance and ED Facility Resources

Studies in health technology and informaticsTan, Dyllon, Cespedes, Marcela, Hassanzadeh, Hamed et al.15 July 2026DOI

Clinical Snapshot

45CEBM
Evidence: WeakRandomised Controlled Trial

PICO Framework

P — PopulationEmergency department patients presenting via ambulance or walk-in at a 250-bed Australian hospital (2021–2022), with 19,570 ambulance records
I — InterventionDigital twin (DT) based on a discrete event simulation (DES) algorithm integrating ambulance arrivals, walk-in presentations, patient off-stretcher time (POST), ambulance bay occupancy, and treatment space (TS) capacity across a 24-hour period
C — ComparatorVaried treatment space capacity scenarios: 43 TS (baseline), 38 TS, and 34 TS, each with five ambulance bays — no real-world control or prospective comparator arm
O — OutcomesPatterns of treatment space depletion and recovery over 24 hours; patient off-stretcher time; ambulance bay occupancy; identification of scenarios where TS recovery failed within 24 hours; sensitivity of patient flow to resource constraints

Bottom Line

This simulation study from CSIRO Queensland presents a digital twin framework for emergency department capacity planning that, for the first time in this modelling lineage, jointly models ambulance and walk-in patient streams alongside fixed treatment space constraints. Calibrated against nearly 20,000 ambulance records from a 250-bed Australian hospital, the model demonstrates that reducing treatment space capacity from 43 to 34 bays can precipitate failure to recover available treatment space within a 24-hour operational cycle — a finding with direct implications for ambulance ramping and patient off-stretcher time. The study is methodologically appropriate for its question and operationally relevant to Australian ED administrators and health planners. However, it carries important limitations: single-site derivation, absence of model validation against independent data, no uncertainty quantification, and a focus on operational rather than patient-centred outcomes. The 2021–2022 calibration period may also reflect COVID-era utilisation patterns. Clinicians and health service managers should view this as a promising proof-of-concept planning tool requiring multi-site validation and integration of patient acuity and staffing variables before broad deployment. The framework aligns well with Australian NEAT targets and state-level ambulance ramping reduction strategies.

Evidence: Weak

Key Findings

  • P Value: Not applicable — simulation study; no formal statistical hypothesis testing reported

  • Effect Size: Not formally quantified; results reported as qualitative patterns of depletion and recovery. Reduction from 43 to 34 TS (a 21% capacity reduction) was associated with failure to recover TS availability within the 24-hour simulation window

  • Primary Outcome: Patterns of treatment space (TS) depletion and recovery over a 24-hour period under three capacity scenarios (43, 38, and 34 TS) with five ambulance bays, including identification of scenarios where TS recovery failed to occur within 24 hours

  • Nnt Or Sensitivity: Not applicable in traditional sense; the key operational metric is patient off-stretcher time (POST) and ambulance bay occupancy as proxies for system performance. Specific POST values not reported in abstract

  • Confidence Interval: Not reported

Clinical Application

Implementation of a digital twin requires sustained data infrastructure investment, including real-time or near-real-time feeds from ambulance dispatch systems, ED information systems, and bed management platforms. This is feasible within well-resourced metropolitan health networks but may be challenging in regional or rural settings. The DES algorithm itself is described as established, suggesting the computational component is not a primary barrier. Highly relevant to the Australian context. Ambulance ramping and ED overcrowding are recognised national patient safety priorities, with the Australian Commission on Safety and Quality in Health Care and state health departments actively seeking capacity planning solutions. The study was conducted using Queensland hospital data by CSIRO, directly informing Australian health system planning. There are no PBS or TGA regulatory considerations for this type of modelling tool. RACGP and ACEM (Australasian College for Emergency Medicine) guidelines on ED access and flow are relevant benchmarks. The National Emergency Access Target (NEAT) — requiring 90% of ED patients to be admitted, discharged, or transferred within four hours — provides a policy framework within which this tool's outputs should be interpreted. State-level ambulance ramping data (particularly prominent in Queensland, Western Australia, and Victoria) underscores the operational urgency of this research. Emergency departments with mixed ambulance and walk-in presentations, particularly those operating near or at treatment space capacity. Most directly applicable to mid-sized Australian public hospitals (200–300 beds) with high ambulance demand.

Abstract

Emergency department (ED) walk-ins and ambulance arrivals are often modelled independently, overlooking their interdependence and the impact of fixed treatment space (TS) capacity. An established discrete event simulation algorithm has been tailored as the basis of a digital twin (DT). Driven by regular streams of incoming ED presentations, patient off-stretcher time (POST), ambulance bay and TS occupation across a 24-hour period contingent on patient flow and ED TS capacity was simulated. The simulation was calibrated using 19,570 ambulance records and data from a 250-bed hospital (2021-2022). Scenarios of five ambulance bays with 43, 38, and 34 TS capacities were investigated, revealing patterns of TS depletion and recovery, including cases where recovery failed within 24 hours, underscoring the sensitivity of patient flow to resource constraints and the value of DT-based simulation for capacity planning.

References

  1. 1.Tan, D., Cespedes, M., Hassanzadeh, H., Riahi, V., & Khanna, S. (2026). Digital Twins for Decision Making: Combining Ambulance and ED Facility Resources. Studies in Health Technology and Informatics. https://doi.org/10.3233/SHTI260965
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