Research Appraisalobservational

Comparison of patient characteristics and health outcomes between self-selected centre-based cardiac rehabilitation and hybrid cardiac telerehabilitation: a prospective cohort study

European journal of preventive cardiologyEser, Prisca, Pini, Matteo, Vetsch, Thomas et al.22 Apr 2026DOI

Clinical Snapshot

70CEBM
Evidence: Moderateobservational

PICO Framework

P — PopulationConsecutive patients with cardiovascular diseases enrolled at a tertiary centre (n=406, 21% female, mean age 60.4±12.7 years)
I — InterventionHybrid cardiac telerehabilitation (hCTR) with home-based exercise monitored by fitness trackers and biosensor vest
C — ComparatorCentre-based cardiac rehabilitation (cbCR) with supervised exercise training sessions
O — OutcomesChanges in exercise capacity (peak VO2), anxiety, depression, health-related quality of life, achievement of blood pressure, LDL-cholesterol, and HbA1c targets

Bottom Line

This prospective cohort study suggests that hybrid cardiac telerehabilitation produces similar functional and mental health outcomes to traditional centre-based programs in cardiovascular patients. However, the study is limited by self-selection bias, with healthier, younger patients preferring the hybrid approach. Centre-based rehabilitation achieved better lipid control, possibly due to more intensive counselling. While telerehabilitation offers promise for improving access to cardiac rehabilitation, particularly in rural settings, the selection bias limits our ability to determine true equivalence. Clinicians should consider patient characteristics when recommending modalities, and ensure robust lipid management protocols for telerehabilitation programs. The findings support offering both modalities based on patient preference and clinical suitability, but randomised controlled trials are needed to establish true therapeutic equivalence.

Evidence: Moderate

Key Findings

  • P Value: Not reported in abstract

  • Effect Size: Peak VO2 baseline difference: 91% vs 80% predicted (hCTR vs cbCR)

  • Primary Outcome: Similar improvements in exercise capacity, anxiety, depression, and health-related quality of life between both groups

  • Nnt Or Sensitivity: LDL-C Step I target achievement: 56% (hCTR) vs 69% (cbCR)

  • Confidence Interval: Not reported in abstract

Clinical Application

Requires fitness trackers, biosensor technology, and telehealth infrastructure - feasible in Australian metropolitan centres Relevant to Australian cardiac rehabilitation services, particularly given Medicare telehealth provisions post-COVID. May support rural/remote access to CR programs Cardiovascular patients suitable for cardiac rehabilitation with access to digital monitoring technology

Abstract

AIMS: Data on self-selected modes of delivery of cardiac rehabilitation (CR) are limited. This study compared centre-based CR (cbCR) with hybrid cardiac telerehabilitation (hCTR) in terms of patient characteristics, change in physical and mental functioning, and achievement of guideline-directed treatment targets. METHODS AND RESULTS: From May 2022 to December 2023, consecutive patients with cardiovascular diseases were enrolled at a tertiary centre into a 3 month cbCR or hCTR programme based on shared decision-making. Changes in exercise capacity, anxiety, depression, and health-related quality of life (hrQoL) scores from admission to the discharge visit were compared between CR modalities. The achievement of two-step blood pressure and LDL-cholesterol (LDL-C) goals, as well as the HbA1c goal in patients with diabetes at the discharge visit, was compared between CR modalities. Out of 1292 patients screened, 406 (21% females, age 60.4 ± 12.7 years) were eligible and completed the study. Of those, 72% chose cbCR and 28% chose hCTR. Patients in hCTR were 3 years younger and exhibited higher baseline peak VO2 (91 vs. 80% of predicted), better hrQoL, and lower depression and anxiety scores. No significant differences were found in improvements in physical or mental functioning or in meeting blood pressure and HbA1c targets between the two groups. A smaller proportion of hCTR participants achieved the LDL-C Step I target (56 vs. 69% in cbCR). CONCLUSION: Overall, hCTR attracted slightly younger patients with better baseline health, but both modalities showed similar effects on most health outcomes. Centre-based cardiac rehabilitation was associated with tighter lipid control, which could be related to more intense counselling or patient preference. Outpatient cardiovascular rehabilitation was equally effective when performed with thrice weekly supervised exercise training sessions or partly performed at home while monitored with fitness trackers and a biosensor vest. Patients who self-select digitally monitored home training were slightly younger, fitter, and had better quality of life with lower levels of anxiety and depression. Blood lipid control, weight loss, and smoking cessation therapies need to be enhanced by tighter control and more intensive medical therapy particularly in patients choosing to perform part of the exercise sessions at home.

References

  1. 1.Eser, P., Pini, M., Vetsch, T., Marcin, T., Berni, S., Burri, R., Casanova, F., Huber, S., Gurschler, F., Boeni, C., Hubli, M., Herwegh, N., Zimmermann, A., Hess, L., Schmutz, S., & Wilhelm, M. (2026). Comparison of patient characteristics and health outcomes between self-selected centre-based cardiac rehabilitation and hybrid cardiac telerehabilitation: a prospective cohort study. European Journal of Preventive Cardiology. https://doi.org/10.1093/eurjpc/zwaf107
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