Research Appraisaldiagnostic

Comparison of CATCH, PECARN and CHALICE rules in children with minor head trauma

European journal of trauma and emergency surgery : official publication of the European Trauma SocietyFerhatlar, Mehmet Esat, Cumhur, Bilgehan Ahmet, Koca, Yavuzselim et al.15 Apr 2026DOI

Clinical Snapshot

60CEBM
Evidence: Moderatediagnostic

PICO Framework

P — PopulationPediatric patients (infants to adolescents) presenting with minor head trauma to a rural secondary-level emergency department
I — InterventionPECARN, CATCH, and CHALICE clinical decision rules
C — ComparatorHead-to-head comparison of the three clinical decision rules
O — OutcomesDiagnostic accuracy (sensitivity, specificity) for detecting pathological brain CT findings

Bottom Line

This prospective study of 1,032 children with minor head trauma compared three clinical decision rules for predicting pathological brain CT findings. PECARN demonstrated perfect sensitivity (100%) but poor specificity (52.1%), meaning it missed no significant injuries but led to many unnecessary CT scans. CATCH showed 93.3% sensitivity and 53.3% specificity, missing one pathological case. CHALICE achieved the best specificity (87.8%) but lowest sensitivity (86.7%), missing two cases while substantially reducing unnecessary imaging. The study suggests PECARN is safest for ruling out significant injury but increases radiation exposure and healthcare costs. CHALICE offers the best balance for reducing unnecessary CT scans but carries small risk of missing pathology. The choice between rules should consider local resources, specialist availability, and acceptable risk tolerance. However, the study lacks methodological detail and confidence intervals, limiting confidence in precise estimates.

Evidence: Moderate

Key Findings

  • P Value: p < 0.05 considered significant (specific values not provided)

  • Effect Size: PECARN: 100% sensitivity, 52.1% specificity; CATCH: 93.3% sensitivity, 53.3% specificity; CHALICE: 86.7% sensitivity, 87.8% specificity

  • Primary Outcome: Diagnostic accuracy for detecting pathological brain CT findings

  • Nnt Or Sensitivity: PECARN achieved 100% sensitivity but with highest false-positive rate; CHALICE had best specificity (87.8%) but missed 2 cases

  • Confidence Interval: Not reported

Clinical Application

All three rules are clinically feasible, requiring only clinical assessment without additional testing Highly relevant to Australian emergency departments, particularly rural and regional centres with limited specialist access. Aligns with RACGP guidelines emphasising evidence-based decision-making in pediatric head trauma Pediatric patients with minor head trauma presenting to emergency departments, particularly relevant for resource-limited settings

Abstract

PURPOSE: The aim of this study is to prospectively compare the diagnostic performance of the PECARN, CATCH, and CHALICE clinical decision rules in pediatric patients presenting with minor head trauma, within a rural secondary-level emergency department characterized by limited resources, high patient volume, and restricted access to specialist physicians. METHODS: The study was designed as a prospective observational study. The PECARN, CATCH, and CHALICE clinical decision rules were applied to the patients included in the study, and the data were recorded. The data included in the study were statistically analyzed using the SPSS (Statistical Package for Social Sciences; SPSS Inc., Chicago, IL) 27 program. A value of p < 0.05 was considered statistically significant. RESULTS: A total of 1,032 patients were included in the study. The PECARN did not miss any of the 15 patients with pathological brain CT and had 100% sensitivity and 52.1% specificity. CATCH failed to detect pathological brain CT in 1 patient and had 93.3% sensitivity and 53.3% specificity. CHALICE failed to detect pathological brain CT in 2 patients, with 86.7% sensitivity and 87.8% specificity. Overall, PECARN was more successful in detecting pathological brain CT, but it also had a high false-positive brain CT rate. CONCLUSION: PECARN criteria are more sensitive than other criteria in predicting brain CT pathology, but they lead to a large number of brain CT scans. While the CHALICE criteria are beneficial in reducing unnecessary brain CT scans, they may miss positive cases.

References

  1. 1.Ferhatlar, M. E., Cumhur, B. A., Koca, Y., Bozan, O., & Kalkan, A. (2026). Comparison of CATCH, PECARN and CHALICE rules in children with minor head trauma. European Journal of Trauma and Emergency Surgery. https://doi.org/10.1007/s00068-021-01859-x
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