Research AppraisalSystematic Review

Cognitive behavioural therapeutics for insomnia symptoms in the perimenopause through to the early postmenopausal period

The Cochrane database of systematic reviewsBreitinger-Blatt, Dani, Lee, Julinda, Ribeiro Pereira, Sofia Isabel et al.24 Apr 2026DOI

Clinical Snapshot

65CEBM
Evidence: InsufficientSystematic Review

PICO Framework

P — PopulationWomen in perimenopause through to early postmenopausal period
I — InterventionCognitive behavioural therapy for insomnia (CBT-I) and cognitive behavioural therapy for menopausal symptoms (CBT-M)
C — ComparatorNot specified in protocol
O — OutcomesPrimary: sleep disturbances; Secondary: vasomotor symptoms, health equality impacts

Bottom Line

This Cochrane protocol outlines a planned systematic review examining cognitive behavioural therapy interventions for sleep disturbances in perimenopausal and early postmenopausal women. The research question is well-focused and addresses a significant clinical need, as sleep problems affect up to 60% of women during menopause transition. The protocol appropriately distinguishes between CBT-I (targeting insomnia specifically) and CBT-M (addressing broader menopausal symptoms). Inclusion of health equity considerations is commendable. However, as this is only a protocol, no evidence synthesis or clinical recommendations are yet available. The completed review will be valuable for informing evidence-based management of menopausal sleep disturbances, particularly given the growing preference for non-hormonal interventions following concerns about hormone replacement therapy risks.

Evidence: Insufficient

Key Findings

  • P Value: Not available - protocol stage

  • Effect Size: Not available - protocol stage

  • Primary Outcome: Sleep disturbances - not yet measured

  • Nnt Or Sensitivity: Not available - protocol stage

  • Confidence Interval: Not available - protocol stage

Clinical Application

CBT interventions are feasible in Australian healthcare settings with trained psychologists Relevant to Australian practice - CBT available through Medicare with GP referral, aligns with RACGP menopause guidelines emphasising non-pharmacological approaches Women experiencing sleep disturbances during perimenopause and early postmenopause

Abstract

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: Primary Objective i) To assess the effects of cognitive behavioural therapy for insomnia (CBT-I) and cognitive behavioural therapy for menopausal symptoms (CBT-M) on sleep disturbances in women in perimenopause through to the early postmenopausal period. Secondary Objectives i) To assess the effects of CBT-I and CBT-M on vasomotor symptoms in women in perimenopause through to the early postmenopausal period. ii) To assess the impact of socioeconomic status on the effectiveness of CBT-I and CBT-M, in order to determine the interventions' impact on health equality.

References

  1. 1.Breitinger-Blatt, D., Lee, J., Ribeiro Pereira, S. I., Smith, C., Gavriloff, D., & Sekaran, S. (2026). Cognitive behavioural therapeutics for insomnia symptoms in the perimenopause through to the early postmenopausal period. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.CD016349
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