Automating data extraction in meta-research: A multi-model benchmark in network psychometrics papers
Clinical Snapshot
PICO Framework
| P — Population | 43 network psychometrics research papers |
| I — Intervention | Five large language models (Claude 4.6 Opus, Claude 4.5 Sonnet, Claude 4.5 Haiku, GPT-5.2, and GPT-5 mini) for automated data extraction |
| C — Comparator | Manual data extraction (implied standard) |
| O — Outcomes | Extraction accuracy (79.6% to 91.3%), cost-effectiveness, processing efficiency, and ability to convey uncertainty |
Bottom Line
This benchmark study demonstrates that current large language models can achieve 79.6-91.3% accuracy in extracting meta-research data from scientific papers, with better performance on explicit information versus subjective inferences. While promising for reducing the time and cost burden of systematic reviews, the study's limitation to network psychometrics papers and lack of robust validation methodology limit confidence in broader applicability. The approach shows particular promise for high-volume data extraction tasks, but human oversight remains essential, especially for complex inferences. Australian researchers should consider this technology as a supplementary tool rather than replacement for traditional systematic review methods, particularly given the need for compliance with NHMRC guidelines requiring rigorous quality assessment.
Key Findings
P Value: Not reported
Effect Size: 12-point accuracy range between best and worst performing models
Primary Outcome: LLM extraction accuracy ranged from 79.6% to 91.3% across five models
Nnt Or Sensitivity: Higher accuracy for explicit verbatim information versus subjective inferences
Confidence Interval: Not reported
Clinical Application
High feasibility with API access; requires technical expertise for implementation Relevant for Australian research institutions conducting meta-analyses; could support NHMRC systematic review guidelines and reduce research costs Meta-researchers and systematic reviewers in psychology and related fields
Abstract
Manual data extraction in meta-research is often tedious, time-consuming, and error-prone. In this paper, we investigate whether the current generation of large language models (LLMs) can be used to extract accurate information from scientific papers. Across the meta-research literature, these tasks usually range from extracting verbatim information (e.g., the number of participants in a study, effect sizes, or whether a study is preregistered) to making subjective inferences. Using a publicly available dataset containing a wide range of metascientific variables from 43 network psychometrics papers, we tested five LLMs (Claude 4.6 Opus, Claude 4.5 Sonnet, Claude 4.5 Haiku, GPT-5.2, and GPT-5 mini). We used an automated API-based pipeline to extract variables from the documents. This approach allows batch processing of research papers. As such, it represents a more efficient and scalable way to extract metascientific data than the default chat interface. The extraction accuracy ranged from 79.6% to 91.3% across the models. The extraction performance was generally higher for more explicit, verbatim information and worse for variables that required more complicated inference. Furthermore, most models were able to convey uncertainty in more contentious cases. We provide a comparison of the accuracy and cost-effectiveness of the individual models and discuss the characteristics of variables that are and are not suitable for automatic coding. Furthermore, we describe some of the common pitfalls and best practices of automated LLM data extraction. The proposed procedure can substantially reduce the time and costs associated with conducting meta-research.
References
- 1.Simsa, B., Buts, A., Ropovik, I., & Adamkovič, M. (2026). Automating data extraction in meta-research: A multi-model benchmark in network psychometrics papers. Behavior Research Methods. https://doi.org/10.1136/bmj-2021-069155
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