Research Appraisaldiagnostic

Automated identification of MRI series using a hierarchical modular machine-learning pipeline

European radiology experimentalKujawa, Mariusz J, Fernández-Patón, Matías, Cerdá Alberich, Leonor et al.28 May 2026DOI

Clinical Snapshot

60CEBM
Evidence: Moderatediagnostic

PICO Framework

P — Population18,181 MRI series from multicentre PRIMAGE repository across multiple anatomical regions
I — InterventionHierarchical modular machine learning pipeline with five sequential classifiers (Family, Weighting, Fat Suppression, Contrast, Others)
C — ComparatorManual annotation/classification (implied reference standard)
O — OutcomesClassification accuracy, sensitivity, specificity, and F1 scores for automated MRI series identification

Bottom Line

This study validates a machine learning pipeline for automated MRI series classification using 18,181 scans from multiple centres. The system achieved excellent accuracy for basic sequence parameters (weighting: 99.4%, family: 98.4%) but struggled with contrast detection (84.1%). While methodologically sound with appropriate cross-validation, the study lacks critical diagnostic accuracy metrics like sensitivity and specificity, and doesn't clearly describe the reference standard. The tool addresses a genuine clinical workflow need for automated MRI cataloguing, potentially reducing radiologist workload in large archives. However, the contrast classification limitation and absence of comparison with existing methods limit immediate clinical implementation. Further validation with clearer reference standards and comprehensive diagnostic metrics would strengthen the evidence base.

Evidence: Moderate

Key Findings

  • P Value: Not reported

  • Effect Size: Weighted F1 score of 0.849 (95% CI: 0.837-0.861)

  • Primary Outcome: Overall classification accuracy of 0.853 (95% CI: 0.841-0.865)

  • Nnt Or Sensitivity: Individual module accuracies: Weighting 0.994, Family 0.984, Fat suppression 0.959, Others 0.958, Contrast 0.841

  • Confidence Interval: 95% CI: 0.837-0.861 for F1 score

Clinical Application

Requires technical infrastructure for machine learning deployment and DICOM processing capabilities Relevant for Australian radiology practices managing large imaging datasets; could support TGA-regulated AI medical devices if validated for clinical use Radiology departments with large MRI archives requiring automated series classification

Abstract

OBJECTIVE: The volume and diversity of large MR imaging datasets require efficient automated labelling tools for cataloguing MR series, as manual annotation is impractical and costly. However, relying on DICOM header fields alone is unreliable because sequence descriptors are heterogeneous and locally defined, frequently missing or incorrect, and may be altered or removed during anonymisation. MATERIALS AND METHODS: We developed an AI-based modular model to classify MR series. The pipeline comprises five sequential classifiers (Family, Weighting, Fat Suppression, Contrast, and Others) and was trained and tested on 18,181 MRI series from the multicentre PRIMAGE repository. The dataset was split by patient into 80% training/validation and 20% testing; within the training/validation subset, five-fold cross-validation was used. With the exception of contrast classification, all modules used DICOM tag-based machine learning models (CatBoost/Random Forest), while the Contrast classifier incorporated image analysis using a pretrained single-slice ResNet-50. Ethical approval for the study was obtained. RESULTS: Accuracy was 0.994 for Weighting, 0.984 for Family, 0.959 for Fat suppression and 0.958 for Others; the Contrast classifier recorded 0.841. Overall, the end-to-end classification yielded a weighted F1 of 0.849 (CI: 0.837-0.861) and an accuracy of 0.853 (CI: 0.841-0.865). CONCLUSION: The proposed approach provides a reliable and scalable solution for labelling large, heterogeneous MRI datasets across multiple anatomical regions. The pipeline achieved excellent performance for Weighting and Family classification, solid performance for Fat Suppression and 'Others'. However, Contrast classification remains the main limitation and warrants further refinement and/or additional modules. RELEVANCE STATEMENT: Reliable, automated MRI sequence labelling enables faster, reproducible cohort selection and protocol harmonisation in large archives, supporting downstream clinical research and AI tools while reducing manual curation effort and error. KEY POINTS: Multicentre PRIMAGE cohort (18,181 MR series) enabling evaluation in a heterogeneous setting. Machine learning model combining DICOM metadata and image features. High accuracy in series classification: up to 0.994 on key tasks. A scalable pipeline reduces manual annotation workload for radiologists.

References

  1. 1.Kujawa, M. J., Fernández-Patón, M., Cerdá Alberich, L., Veiga-Canuto, D., & Martí-Bonmatí, L. (2026). Automated identification of MRI series using a hierarchical modular machine-learning pipeline. European Radiology Experimental, 8, Article 214. https://doi.org/10.1186/s41747-021-00214-4
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