Research Appraisaldiagnostic

AI-Assisted Lung Sliding Detection in Point-of-Care Ultrasound by Marine Corps Corpsmen: A Multi-Reader Study

Journal of special operations medicine : a peer reviewed journal for SOF medical professionalsCote, Melissa, Prager, Ross, Tran, Khoa et al.3 Apr 2026DOI

Clinical Snapshot

60CEBM
Evidence: Weakdiagnostic

PICO Framework

P — PopulationFive United States Marine Corps Corpsmen, all novices in point-of-care ultrasound
I — InterventionAI-assisted lung ultrasound interpretation using ATLAS system (Deep Breathe Inc.)
C — ComparatorUnassisted lung ultrasound interpretation (control)
O — OutcomesDiagnostic accuracy for detecting absent lung sliding (AUROC, sensitivity, specificity, accuracy) and reader confidence ratings

Bottom Line

This small pilot study suggests AI assistance can significantly improve novice military medics' ability to detect absent lung sliding on ultrasound, a key finding for pneumothorax diagnosis. The AI system improved diagnostic accuracy from 67% to 88% and increased reader confidence. However, the study's major limitations include very small sample size (5 readers), insufficient methodological detail, and unclear generalizability beyond the specific AI system tested. While promising for military and resource-limited settings, larger validation studies with diverse populations and clinical scenarios are needed before widespread implementation. The technology shows potential but requires further rigorous evaluation before clinical adoption.

Evidence: Weak

Key Findings

  • P Value: P=0.03 for AUROC improvement; P<0.001 for accuracy measures

  • Effect Size: AUROC improved from 0.72 to 0.93 with AI assistance

  • Primary Outcome: Area under receiver operating characteristic curve (AUROC)

  • Nnt Or Sensitivity: Sensitivity: 0.90 (SD 0.09), Specificity: 0.86 (SD 0.10) with AI assistance

  • Confidence Interval: Not reported

Clinical Application

Requires AI software integration with portable ultrasound systems; feasibility in austere environments unclear Relevant for Australian Defence Force medics, rural/remote practitioners, and emergency services where ultrasound expertise is limited Military medics and other healthcare providers with limited ultrasound training in resource-limited settings

Abstract

BACKGROUND: Artificial intelligence (AI) has the potential to address training limitations and inter-operator variability that constrain the use of lung ultrasound (LUS) in austere and prehospital settings. This pilot study evaluated whether AI-based decision support could improve the diagnostic accuracy and confidence of United States Marine Corps Corpsmen in identifying absent lung sliding, a key indicator of pneumothorax, during LUS interpretation. METHODS: This pilot-prospective multi-reader, multi-case study involved five military medics, all novices in point-of-care ultrasound, each interpreting 50 de-identified LUS video clips twice, once without AI assistance (control) and once with AI assistance (ATLAS, Deep Breathe Inc., London, Canada), in randomized order with at least a 2-hour washout between sessions. Expert consensus served as a reference standard. Diagnostic performance was assessed using area under the receiver operating characteristic curve (AUROC), sensitivity, specificity, and accuracy. Differences were analyzed using the Random-Reader Random-Case method. Per-clip reader confidence ratings were compared using the Stuart-Maxwell test. RESULTS: AI assistance significantly improved diagnostic performance across all measured outcomes. The mean AUROC increased from 0.72 (SD 0.16) without AI to 0.93 (SD 0.04) with AI (P=.03). Sensitivity rose from 0.63 (SD 0.14) to 0.90 (SD 0.09), specificity from 0.70 (SD 0.15) to 0.86 (SD 0.10), and overall accuracy from 0.67 (SD 0.10) to 0.88 (0.06) (McNemar's test, P<.001). Reader confidence also improved, with high-confidence ratings nearly doubling from 20% to 37%, and low-confidence ratings decreasing from 38% to 33%. These distributional changes were statistically significant (Stuart-Maxwell χ², P<.001). CONCLUSION: AI support markedly improved the diagnostic accuracy and confidence of novice LUS interpretation for detecting absent lung sliding. These findings suggest that real-time AI-based decision support may help improve access to high-quality LUS in military and other resource-limited care settings.

References

  1. 1.Cote, M., Prager, R., Tran, K., Orozco, N., Smith, D., Holliday, Z., & Arntfield, R. (2026). AI-assisted lung sliding detection in point-of-care ultrasound by Marine Corps corpsmen: A multi-reader study. Journal of Special Operations Medicine, Article 1SDN-NWTW. https://doi.org/10.55460/J.Spec.Oper.Med.2026.1SDN-NWTW
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