A Temperature-Pressure Dual-Mode Flexible Patch Sensor with Temperature Compensation and Pressure Decoupling Functions for Pulse Detection and Recognition

Clinical Snapshot

Key Findings

• P Value: Not provided in abstract

• Effect Size: Pressure detection range: 50 Pa-200 kPa

• Primary Outcome: Pulse wave classification accuracy of 97.6% with ResNet-based model

• Nnt Or Sensitivity: Temperature resolution: 0.1°C, Response time: 60ms, Recovery time: 96ms

• Confidence Interval: Not provided in abstract

Clinical Application

High feasibility for wearable health monitoring applications Relevant for TGA medical device approval pathway, potential integration with existing telehealth initiatives, applicable to RACGP chronic disease management programs Patients requiring continuous pulse monitoring, athletes, individuals with cardiovascular conditions

Abstract

Accurate and continuous detection of human pulse waves is critical for long-term health monitoring and physiological assessment during physical activity. However, most conventional flexible pulse sensors are single-mode, making them susceptible to interference from both ambient and physiological temperature fluctuations. Developing integrated dual-mode sensors remains challenging due to the difficulty in effectively decoupling pressure and temperature signals. Herein, we report a dual-mode flexible patch sensor featuring a unique "compass-like" structural design. The sensor demonstrates a broad pressure detection range (50 Pa-200 kPa) and rapid response/recovery times (60/96 ms), while its integrated temperature-sensing unit achieves a high resolution of 0.1 °C. Through unique structural design, the sensor achieves robust pressure decoupling of the temperature signal, with resistance fluctuations of only 0.102% under pressures up to 30 kPa. This independent temperature signal is subsequently utilized as a reference for the real-time temperature compensation of the pressure signal. The compensated pressure signal exhibits minimal temperature drift (41 × 10-6 °C-1 across 5-45 °C), enabling stable, interference-resistant monitoring of radial artery pulse waves under dynamic thermal conditions. Furthermore, when integrated with a ResNet-based deep learning model, the sensor successfully classifies diverse pulse signals with an accuracy of 97.6%. This research provides an effective solution for interference-resistant wearable electronics, offering significant potential for intelligent disease diagnosis and sports health management.

References

1. 1.Ma, Y., Zhao, W., Yan, R., Duan, X., Cheng, H., Zhang, J., Guo, H., Xiao, Y., Su, D., Chen, Y., Xu, D., & Chen, M. (2026). A Temperature-Pressure Dual-Mode Flexible Patch Sensor with Temperature Compensation and Pressure Decoupling Functions for Pulse Detection and Recognition. ACS Sensors. https://doi.org/10.1021/acssensors.5c04432