Withdrawn AI Sepsis Prediction Trial Highlights Critical Need for Postoperative Monitoring Solutions
247 Health News Editorial
·11 Apr 2026
·3 min read
·clinical-trialsA withdrawn Greek trial aimed to develop AI-driven sepsis prediction for postoperative abdominal surgery patients using continuous monitoring. Despite withdrawal, the concept highlights critical needs in surgical ward surveillance.
Originally reported by ClinicalTrials.gov
References
- 1.Aisthesis Medical P.C. (2024). Prediction of Sepsis in Patients Undergoing Abdominal Surgery: A Prospective, Observational Clinical Study. ClinicalTrials.gov. NCT06238180. https://clinicaltrials.gov/study/NCT06238180
- 2.Singer, M., Deutschman, C. S., Seymour, C. W., Shankar-Hari, M., Annane, D., Bauer, M., Bellomo, R., Bernard, G. R., Chiche, J. D., Coopersmith, C. M., Hotchkiss, R. S., Levy, M. M., Marshall, J. C., Martin, G. S., Opal, S. M., Rubenfeld, G. D., van der Poll, T., Vincent, J. L., & Angus, D. C. (2016). The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA, 315(8), 801-810. https://doi.org/10.1001/jama.2016.0287
- 3.Churpek, M. M., Yuen, T. C., Winslow, C., Meltzer, D. O., Kattan, M. W., & Edelson, D. P. (2016). Multicenter comparison of machine learning methods and conventional regression for predicting clinical deterioration on the wards. Critical Care Medicine, 44(2), 368-374. https://doi.org/10.1097/CCM.0000000000001571
- 4.Fleischmann-Struzek, C., Mellhammar, L., Rose, N., Cassini, A., Rudd, K. E., Schlattmann, P., Machado, F. R., & Reinhart, K. (2020). Incidence and mortality of hospital- and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis. Intensive Care Medicine, 46(8), 1552-1562. https://doi.org/10.1007/s00134-020-06151-x
- 5.Kumar, A., Roberts, D., Wood, K. E., Light, B., Parrillo, J. E., Sharma, S., Suppes, R., Feinstein, D., Zanotti, S., Taiberg, L., Gurka, D., & Cheang, M. (2006). Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Critical Care Medicine, 34(6), 1589-1596. https://doi.org/10.1097/01.CCM.0000217961.75225.E9
- 6.Alam, N., Hobbelink, E. L., van Tienhoven, A. J., van de Ven, P. M., Jansma, E. P., & Nanayakkara, P. W. (2014). The impact of the use of the Early Warning Score (EWS) on patient outcomes: a systematic review. Resuscitation, 85(5), 587-594. https://doi.org/10.1016/j.resuscitation.2014.03.013
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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