Health Technology/clinical-trials

Validation Study Opens: AI-Based Assessment vs Sunnybrook Scale in Bell's Palsy — Potential for Objective Facial Nerve Monitoring

247 Health News Editorial

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13 May 2026

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4 min read

·clinical-trials

Cairo University launches validation study comparing AI-based facial assessment with traditional Sunnybrook grading in Bell's palsy patients. This research could revolutionise objective facial nerve monitoring and eliminate inter-observer variability in clinical practice.

Originally reported by ClinicalTrials.gov

References

  1. 1.Baugh, R. F., Basura, G. J., Ishii, L. E., Schwartz, S. R., Drumheller, C. M., Burkholder, R., ... & Thomas, N. J. (2013). Clinical practice guideline: Bell's palsy. Otolaryngology-Head and Neck Surgery, 149(3_suppl), S1-S27. https://doi.org/10.1177/0194599813505967
  2. 2.Cairo University. (2024). Validation of Artificial Intelligence-Based Facial Paralysis Assessment in Patients With Bell's Palsy. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07573358
  3. 3.Fattah, A. Y., Gurusinghe, A. D., Gavilan, J., Hadlock, T. A., Marcus, J. R., Marres, H., ... & Jowett, N. (2015). Facial nerve grading instruments: systematic review of the literature and suggestion for uniformity. Plastic and Reconstructive Surgery, 135(2), 569-579. https://doi.org/10.1097/PRS.0000000000001114
  4. 4.Grogan, P. M., & Gronseth, G. S. (2001). Practice parameter: steroids, acyclovir, and surgery for Bell's palsy (an evidence-based review). Neurology, 56(7), 830-836. https://doi.org/10.1212/WNL.56.7.830
  5. 5.Hohman, M. H., & Hadlock, T. A. (2014). Etiology, diagnosis, and management of facial palsy: 2000 patients at a facial nerve center. Laryngoscope, 124(7), E283-E293. https://doi.org/10.1002/lary.24542
  6. 6.House, J. W., & Brackmann, D. E. (1985). Facial nerve grading system. Otolaryngology-Head and Neck Surgery, 93(2), 146-147. https://doi.org/10.1177/019459988509300202
  7. 7.Neely, J. G., Cherian, N. G., Dickerson, C. B., & Nedzelski, J. M. (2010). Sunnybrook facial grading system: reliability and criteria for grading. Laryngoscope, 120(5), 1038-1045. https://doi.org/10.1002/lary.20868
  8. 8.Peitersen, E. (2002). Bell's palsy: the spontaneous course of 2,500 peripheral facial nerve palsies of different etiologies. Acta Oto-Laryngologica, 122(7), 4-9. https://doi.org/10.1080/000164802760370736
  9. 9.Ross, B. G., Fradet, G., & Nedzelski, J. M. (1996). Development of a sensitive clinical facial grading system. Otolaryngology-Head and Neck Surgery, 114(3), 380-386. https://doi.org/10.1016/S0194-5998(96)70175-5
  10. 10.Zhang, W., Xu, L., Luo, T., Wu, F., Zhao, B., & Li, X. (2020). The etiology of Bell's palsy: a review. Journal of Neurology, 267(7), 1896-1905. https://doi.org/10.1007/s00415-019-09282-4
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