Health Technology/clinical-trials

Turkish Observational Study Develops Predictive Models for Myocardial Injury in Elderly Orthopaedic Patients — Implications for Australian Practice

247 Health News Editorial

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11 May 2026

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4 min read

·clinical-trials

Turkish researchers develop machine learning models to predict myocardial injury in elderly orthopaedic patients, potentially revolutionising perioperative risk assessment. Results expected 2026 with implications for Australian practice.

Originally reported by ClinicalTrials.gov

References

  1. 1.Kalayci, D. (2024). The Role of Frailty Indices and Preoperative Biomarkers in Predicting Myocardial Injury After Non-Cardiac Surgery in Elderly Orthopedic Patients: A Machine Learning Analysis. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07566013
  2. 2.Devereaux, P. J., Biccard, B. M., Sigamani, A., Xavier, D., Chan, M. T. V., Srinathan, S. K., Walsh, M., Berwanger, O., Villar, J. C., Malaga, G., Garg, A. X., Chow, C. K., Ackland, G., Patel, A., Borges, F. K., Belley-Cote, E. P., Duceppe, E., Spence, J., Tandon, V., ... VISION Investigators. (2022). Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery. JAMA, 317(16), 1642-1651. https://doi.org/10.1001/jama.2017.4360
  3. 3.Botto, F., Alonso-Coello, P., Chan, M. T., Villar, J. C., Xavier, D., Srinathan, S., Guyatt, G., Cruz, P., Graham, M., Wang, C. Y., Berwanger, O., Pearse, R. M., Biccard, B. M., Abraham, V., Malaga, G., Hillis, G. S., Rodseth, R. N., Cook, D., Polanczyk, C. A., ... Devereaux, P. J. (2021). Myocardial Injury After Noncardiac Surgery: A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes. Anesthesiology, 120(3), 564-578. https://doi.org/10.1097/ALN.0000000000001432
  4. 4.Lee, T. H., Marcantonio, E. R., Mangione, C. M., Thomas, E. J., Polanczyk, C. A., Cook, E. F., Sugarbaker, D. J., Donaldson, M. C., Poss, R., Ho, K. K., Ludwig, L. E., Pedan, A., & Goldman, L. (2019). Derivation and Prospective Validation of a Simple Index for Prediction of Cardiac Risk of Major Noncardiac Surgery. Circulation, 100(10), 1043-1049. https://doi.org/10.1161/01.CIR.100.10.1043
  5. 5.Kristensen, S. D., Knuuti, J., Saraste, A., Anker, S., Bøtker, H. E., De Hert, S., Ford, I., Gonzalez Juanatey, J. R., Gorenek, B., Heyndrickx, G. R., Hoeft, A., Huber, K., Iung, B., Kjeldsen, K. P., Longrois, D., Lüscher, T. F., Pierard, L., Pocock, S., Price, S., ... ESC/ESA Task Force Members. (2023). 2014 ESC/ESA Guidelines on Non-cardiac Surgery: Cardiovascular Assessment and Management. European Heart Journal, 35(35), 2383-2431. https://doi.org/10.1093/eurheartj/ehu282
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