Telerehabilitation vs In-Person Therapy for Post-Stroke Upper Extremity Recovery: Tele-CPASS Trial Opens Recruitment — What Stroke Clinicians Need to Know
247 Health News Editorial
·8 July 2026
·4 min read
·clinical-trialsA new US randomised trial is testing whether 20 hours of telerehabilitation can match in-person CPASS therapy for upper extremity recovery in the critical early weeks after stroke. The Tele-CPASS trial targets the neuroplasticity window within 40 days of stroke onset, with outcomes tracked to 12 months. Clinicians managing acute stroke patients should be aware of this emerging evidence base for remote rehabilitation delivery.
Originally reported by ClinicalTrials.gov
References
- 1.University of Texas, El Paso. (2025). Efficacy of Tele-CPASS, a telerehabilitation intervention using Critical Periods After Stroke Study (CPASS) compared to in-person CPASS for upper extremity motor recovery (NCT07661849). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07661849
- 2.Dromerick, A. W., Geed, S., Barth, J., Brady, K., Giannetti, M. L., Mitchell, A., Edwardson, M. A., Tan, M. T., Tamboli, I., Chia Bejarano, C., Cheema, J. O., Edwards, D. F., & Newport, E. L. (2021). Critical Period After Stroke Study (CPASS): A phase II clinical trial testing an optimal time for motor recovery after stroke in humans. Proceedings of the National Academy of Sciences, 118(34), e2026676118. https://doi.org/10.1073/pnas.2026676118
- 3.Yozbatiran, N., Der-Yeghiaian, L., & Cramer, S. C. (2008). A standardized approach to performing the action research arm test. Neurorehabilitation and Neural Repair, 22(1), 78–90. https://doi.org/10.1177/1545968307305353
- 4.Kwakkel, G., Kollen, B. J., van der Grond, J., & Prevo, A. J. (2003). Probability of regaining dexterity in the flaccid upper limb: Impact of severity of paresis and time after onset in acute stroke. Stroke, 34(9), 2181–2186. https://doi.org/10.1161/01.STR.0000087172.16305.CD
- 5.Laver, K. E., Adey-Wakeling, Z., Crotty, M., Lannin, N. A., George, S., & Sherrington, C. (2020). Telerehabilitation services for stroke. Cochrane Database of Systematic Reviews, 2020(1), CD010255. https://doi.org/10.1002/14651858.CD010255.pub3
- 6.Langhorne, P., Coupar, F., & Pollock, A. (2009). Motor recovery after stroke: A systematic review. The Lancet Neurology, 8(8), 741–754. https://doi.org/10.1016/S1474-4422(09)70150-4
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247 Health News Editorial
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